FB2026_02 , released June 18, 2026
Allele: Dmel\ldsHD5.1
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General Information
Symbol
Dmel\ldsHD5.1
Species
D. melanogaster
Name
FlyBase ID
FBal0247465
Feature type
allele
Associated gene
Dmel\lds
Associated Insertion(s)
Carried in Construct
P{lds.HD5.1}
Key Links
Transgenic product class
missense_variant
(Szalontai et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Szalontai et al., 2009)
Mutagen
in vitro construct
(Szalontai et al., 2009)
Progenitor genotype
Carried in construct
P{lds.HD5.1}
Cytology
Description

5107bp genomic fragment containing lds which has been mutated to carry the same lesion as in ldsHor-D (amino acid replacement A777T).

(Szalontai et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
lds
Encoded product / tool
lds
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Females carrying ldsHD5.1 are sterile. Cuticle fragment appear inside 28% of eggs derived from these females, but larvae never hatch.

      7.2% of the offspring of males carrying ldsHD5.1 are XX//X0 mosaics.

      (Szalontai et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ldsHD5.1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)