FB2026_02 , released June 18, 2026
Allele: Dmel\bwa2
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General Information
Symbol
Dmel\bwa2
Species
D. melanogaster
Name
FlyBase ID
FBal0248967
Feature type
allele
Associated gene
Dmel\bwa
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Yuan et al., 2011)
Progenitor genotype
P{GawB}bwaP
(Yuan et al., 2011)
Cytology
Description

Imprecise excision of P{GawB}bwaP resulting in the deletion of a 2282 bp fragment removing exons 2 and 3 of bwa. As a consequence, splicing of the first exon to the fourth results in the generation of a truncated peptide containing 47 amino acids of the first exon.

(Yuan et al., 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:20,068,259..20,070,551 [+]
Comment:

Imprecise excision of P{GawB}bwaP resulting in the deletion of a 2282 bp fragment removing exons 2 and 3 of bwa. As a consequence, splicing of the first exon to the fourth results in the generation of a truncated peptide containing 47 amino acids of the first exon.

(Yuan et al., 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous bwa2 mutants are viable and fertile. Flies homozygous for bwa2 exhibit normal life span.

      The cerebral hemispheres of bwa2 homozygotes appear normal, and no fusion is observed between the two hemispheres. Homozygous bwa2 flies show no obvious degeneration of photoreceptors.

      (Yuan et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      bwa2
      (Yuan et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)