FB2026_02 , released June 18, 2026
Allele: Dmel\Cdc45NIG.3658R
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General Information
Symbol
Dmel\Cdc45NIG.3658R
Species
D. melanogaster
Name
FlyBase ID
FBal0249091
Feature type
allele
Associated gene
Dmel\Cdc45
Associated Insertion(s)
Carried in Construct
P{NIG.3658R}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Kondo and Perrimon, 2011)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Kondo and Perrimon, 2011)
Mutagen
in vitro construct
(Kondo and Perrimon, 2011)
Progenitor genotype
Carried in construct
P{NIG.3658R}
Cytology
Description

UASt regulatory sequences drive expression of a CDC45L RNAi construct.

(Kondo and Perrimon, 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-3658R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      X-ray irradiation of wild-type third-instar larvae induces cell cycle arrest within 1 hour. In contrast, X-ray irradiation of larvae expressing CDC45LNIG.3658R via Scer\GAL4ap-md544 fails to induce cell cycle arrest.

      (Kondo and Perrimon, 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CDC45LNIG.3658R
      Cdc45NIG.3658R
      Name Synonyms
      Secondary FlyBase IDs
        References (2)