FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\TTRUAS.Tag:FLAG
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General Information
Symbol
Hsap\TTRUAS.Tag:FLAG
Species
H. sapiens
Name
FlyBase ID
FBal0249333
Feature type
allele
Associated gene
Hsap\TTR
Associated Insertion(s)
Carried in Construct
P{UAS-Hsap\TTR-FLAG}
Key Links
Transgenic product class
cDNA
(Pokrzywa et al., 2010)
wild_type
(Pokrzywa et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Pokrzywa et al., 2010)
wild_type
(Pokrzywa et al., 2010)
Mutagen
in vitro construct
(Pokrzywa et al., 2010)
Progenitor genotype
Hsap\TTRUAS.cPa
(Pokrzywa et al., 2010)
Carried in construct
P{UAS-Hsap\TTR-FLAG}
Cytology
Description

A Tag:FLAG tag is inserted between the Hsap\TTR signal peptide and the rest of the Hsap\TTR sequence.

(Pokrzywa et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\TTR
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The size and organisation of the retina in flies expressing Hsap\TTRScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF appears identical to that of normal control flies independent of age.

      Arrays of nanofilaments 7-9nm in thickness and nanospheres of about 20nm in diameter are abundant in the cytoplasm of glial cells that cover the surface of the retina (subretinal glia) and those that cover the surface of the brain (perineurial glia) in Hsap\TTRScer\UAS.T:Zzzz\FLAG/+ and Hsap\TTRScer\UAS.T:Zzzz\FLAG/Hsap\TTRScer\UAS.T:Zzzz\FLAG (all under the control of Scer\GAL4GMR.PF) flies but not in wild-type flies.

      (Pokrzywa et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\TTRScer\UAS.T:Zzzz\FLAG
      Hsap\TTRUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)