FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Prx3UAS.cRa
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General Information
Symbol
Dmel\Prx3UAS.cRa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Radyuk
FlyBase ID
FBal0249413
Feature type
allele
Associated gene
Dmel\Prx3
Associated Insertion(s)
Carried in Construct
P{UAS-Prx3.R}
Also Known As
UAS-dPrx3
Key Links
Transgenic product class
cDNA
(Radyuk et al., 2010)
wild_type
(Radyuk et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Radyuk et al., 2010)
wild_type
(Radyuk et al., 2010)
Mutagen
in vitro construct
(Radyuk et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Prx3.R}
Cytology
Description

UASt drives expression of a fragment derived from cDNA clone SD08737 comprising the entire coding region of Prx3, 62 bp 5' UTR and 100 bp 3'UTR.

(Radyuk et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Prx3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Prx3Scer\UAS.cRa using Scer\GAL4arm.PS, Scer\GAL4da.G32 or Scer\GAL4αTub84B.PL does not have any significant effect on susceptibility to oxidative stress or longevity.

      Overexpression of Prx3Scer\UAS.cRa using Scer\GAL4Appl.G1a has no effect on longevity, although resistance to oxidative stress is increased particularly in middle-aged (30 day old) flies. However, overexpression of Prx3Scer\UAS.cRa using Scer\GAL4elav-C155 or Scer\GAL4D42 did not confer similar effects.

      (Radyuk et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Prx3Scer\UAS.cRa
      Prx3UAS.cRa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Radyuk
      Secondary FlyBase IDs
        References (3)