FB2026_02 , released June 18, 2026
Allele: Disc\RFPGr66a.PD
Open Close
General Information
Symbol
Disc\RFPGr66a.PD
Species
D. sp.
Name
Gustatory receptor 66a promoter construct of Dahanukar
FlyBase ID
FBal0249463
Feature type
allele
Associated gene
Disc\RFP
Associated Insertion(s)
Carried in Construct
P{Gr66a-RFP.D}
Also Known As
Gr66a-RFP
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Dahanukar et al., 2007)
Progenitor genotype
Carried in construct
P{Gr66a-RFP.D}
Cytology
Description

An approximately 2kb fragment of Gr66a promoter sequences is fused upstream of three copies of the mRFP(Unk) coding region, which are separated from each other by IRES sequences (from the Ubx gene). An SV40 3' UTR is also present.

(Dahanukar et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
Gr66a
Encoded product / tool
mRFP(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      gustatory receptor neuron | subset of labellum
      (Vermehren-Schmaedick et al., 2011)
      adult stage
      gustatory receptor neuron | subset of labellum
      (Vermehren-Schmaedick et al., 2011)
      prothoracic leg taste bristle chemosensory neuron | subset of prothoracic leg
      (Vermehren-Schmaedick et al., 2011)
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      gustatory receptor neuron | subset of short labellar taste bristle | subset
      (Weiss et al., 2011)
      gustatory receptor neuron | subset of intermediate labellar taste bristle | subset
      (Weiss et al., 2011)
      Additional Information
      Statement
      Reference

      DiscRFPGr66a.PD is expressed in gustatory neurons of the bitter-sensitive short labellar taste bristles, and in gustatory neurons of all of the intermediate labellar taste bristles.

      (Weiss et al., 2011)

      DiscRFPGr66a.PD labels the bitter-sensitive neuron of the labellum and the prothoracic leg. It is co-expressed with ScerGAL4Gyc-89Da.1.9 and ScerGAL4Gyc-89Db.3.4 in subsets of gustatory neurons in the labellum.

      (Vermehren-Schmaedick et al., 2011)
       
      Marker for
      Reflects expression of
      Gr66a
      (Vermehren-Schmaedick et al., 2011, Weiss et al., 2011)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Disc\RFPGr66a.PD
      Name Synonyms
      Gustatory receptor 66a promoter construct of Dahanukar
      Secondary FlyBase IDs
        References (8)