FlyBase Allele Report: Dmel\cnn[WT.UASp.EGFP]

General Information

Symbol

Dmel\cnn^WT.UASp.EGFP

Species

D. melanogaster

Name

FlyBase ID

FBal0256920

Feature type

allele

Associated gene

Dmel\cnn

Associated Insertion(s)

Carried in Construct

P{UASp-cnn.WT}

Also Known As

UASp-GFP-Cnn

Key Links

Transgenic product class

inframe_deletion

(Zhang and Megraw, 2007)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Zhang and Megraw, 2007)

Mutagen

in vitro construct

(Zhang and Megraw, 2007)

Progenitor genotype

Carried in construct

P{UASp-cnn.WT}

Cytology

Description

UASp regulatory sequences drive expression of cnn coding sequence (lacking the amino terminal 17 amino acids of the maternal cnn-RA transcript). The cnn sequences are tagged with EGFP.

(Zhang and Megraw, 2007)

Allele components

Component

Use(s)

Regulatory region(s)

UASp

binary expression system - regulatory region

Encoded product / tool

cnn

Tagged with

EGFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile, with Scer\GAL4^αTub84B.PL

(Zheng et al., 2016)

viable, with Scer\GAL4^αTub84B.PL

(Zheng et al., 2016)

Phenotype Manifest In

Detailed Description

Statement

Reference

Flies with overexpression of cnn^{WT.Scer\UAS.T:Avic\GFP-EGFP} driven ubiquitously by Scer\GAL4^αTub84B.PL are healthy and fertile.

(Zheng et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^{VP16.nanos.UTR}/cnn^WT.UASp.EGFP rescues cnn^HK21/cnn^25cn1

(Zhang and Megraw, 2007)

Comments

Expression of cnn^{WT.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} fully rescues the maternal effect lethality of cnn^HK21/cnn^25cn1 embryos.

(Zhang and Megraw, 2007)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

cnn^{WT.Scer\UAS.T:Avic\GFP-EGFP}

cnn^WT.UASp.EGFP

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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