FlyBase Allele Report: Dmel\fabp[HMS01163]

General Information

Symbol

Dmel\fabp^HMS01163

Species

D. melanogaster

Name

FlyBase ID

FBal0257823

Feature type

allele

Associated gene

Dmel\fabp

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01163}

Also Known As

UAS-Dfabp RNAi, uas-fabp RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS01163}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS01163

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates Alzheimer's disease 1

modeled by Hsap\APP^2xAPP.SP.UAS

(Jang et al., 2024)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

abnormal circadian rhythm | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

abnormal locomotor behavior | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

abnormal locomotor behavior | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

abnormal neuroanatomy | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

abnormal neuroanatomy | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

decreased cell number | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

decreased size | adult stage, with Scer\GAL4^Bx-MS1096

(Jang et al., 2022)

decreased size | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

decreased size | adult stage, with Scer\GAL4^GMR.PFa

(Jang et al., 2022)

decreased size | adult stage, with Scer\GAL4^ptc-559.1

(Jang et al., 2022)

decreased size | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

increased cell death | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

increased cell death | adult stage, with Scer\GAL4^repo

(Jang et al., 2022)

increased cell number | adult stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

lethal, with Scer\GAL4^en-e16E

(Jang et al., 2022)

partially lethal, with Scer\GAL4^elav-C155

(Jang et al., 2022)

partially lethal, with Scer\GAL4^repo

(Jang et al., 2022)

some die during embryonic stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

some die during P-stage, with Scer\GAL4^elav-C155

(Jang et al., 2022)

some die during P-stage, with Scer\GAL4^repo

(Jang et al., 2022)

visible | adult stage, with Scer\GAL4^Bx-MS1096

(Jang et al., 2022)

visible | adult stage, with Scer\GAL4^GMR.PFa

(Jang et al., 2022)

visible | adult stage, with Scer\GAL4^ptc-559.1

(Jang et al., 2022)

Phenotype Manifest In

adult brain, with Scer\GAL4^elav-C155

(Jang et al., 2022)

adult brain, with Scer\GAL4^repo

(Jang et al., 2022)

adult CNS glial cell | decreased number, with Scer\GAL4^repo

(Jang et al., 2022)

adult CNS glial cell | increased number, with Scer\GAL4^elav-C155

(Jang et al., 2022)

eye, with Scer\GAL4^GMR.PFa

(Jang et al., 2022)

lobe system of adult mushroom body, with Scer\GAL4^elav-C155

(Jang et al., 2022)

lobe system of adult mushroom body, with Scer\GAL4^repo

(Jang et al., 2022)

wing, with Scer\GAL4^Bx-MS1096

(Jang et al., 2022)

wing, with Scer\GAL4^ptc-559.1

(Jang et al., 2022)

wing hair | decreased number, with Scer\GAL4^ptc-559.1

(Jang et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

34685

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01163}attP2

NIG-Fly

HMS01163

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01163}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

fabp^HMS01163

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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