FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: SV40\STearly.UASp
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General Information
Symbol
SV40\STearly.UASp
Species
P. Simian virus 40
Name
FlyBase ID
FBal0258002
Feature type
allele
Associated gene
SV40\ST
Associated Insertion(s)
Carried in Construct
P{UASp-SV40.early-region}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kotadia et al., 2008)
Progenitor genotype
Carried in construct
P{UASp-SV40.early-region}
Cytology
Description

UASp regulatory sequences are fused upstream of the SV40 early region, which encodes the large tumor antigen, small tumor antigen (SV40\ST) and 17kT proteins. Expression of only the SV40\ST product is detectable in transgenic flies containing this construct.

(Kotadia et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
SV40\ST
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of SV40\STearly.Scer\UAS.P\T under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 causes an increase in centrosome numbers and mitotic spindle abnormalities in early embryos and results in lethality.

      (Kotadia et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SV40\STearly.Scer\UAS.P\T
      SV40\STearly.UASp
      Name Synonyms
      Secondary FlyBase IDs
        References (1)