FB2026_02 , released June 18, 2026
Allele: Dmel\Vps33BRNAi.UAS.WIZ
Open Close
General Information
Symbol
Dmel\Vps33BRNAi.UAS.WIZ
Species
D. melanogaster
Name
FlyBase ID
FBal0258128
Feature type
allele
Associated gene
Dmel\Vps33B
Associated Insertion(s)
Carried in Construct
P{UAS-Vps33B.RNAi.WIZ}
Key Links
Transgenic product class
RNAi_reagent
(Akbar et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Akbar et al., 2011)
Mutagen
in vitro construct
(Akbar et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-Vps33B.RNAi.WIZ}
Cytology
Description

A 381bp inverted repeat (bp 1180-1561) of Vps33B mRNA is cloned into a pWIZ vector under the control of UAS regulatory sequences.

(Akbar et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Vps33B
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Knock-down of Vps33B through expression of Vps33BdsRNA.Scer\UAS.WIZ under the control of Scer\GAL4da.G32 results in elevated levels of bacteria in primary hemocytes, suggesting an inability to digest them.

      Knock-down of Vps33B through expression of Vps33BdsRNA.Scer\UAS.WIZ under the control of Scer\GAL4da.G32 does not affect normal lysosomal function.

      (Akbar et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Vps33BRNAi.UAS.WIZ
      Vps33BdsRNA.Scer\UAS.WIZ
      Vps33BdsRNA.UAS.WIZ
      Name Synonyms
      Secondary FlyBase IDs
        References (2)