FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gr64fUAS.cJa
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General Information
Symbol
Dmel\Gr64fUAS.cJa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Jiao
FlyBase ID
FBal0258334
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Gr64f
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of Gr64f.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Gr64fScer\UAS.cJa in Df(3L)ΔGr64 mutants under the control of Scer\GAL4Gr5a.1 fully restores trehalose sensation in a behavioural assay.

Similarly to wild-type flies, Df(3L)ΔGr64 mutant flies expressing Gr64fScer\UAS.cJa under the control of Scer\GAL4Gr5a.1display high frequencies of action potentials in response to trehalose.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

In contrast to wild-type flies, Df(3L)ΔGr64 mutant flies expressing Gr64fScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 do not show a behavioural preference for sucrose over fructose. In contrast to wild-type flies, the mutant flies display only a minimal increase in action potentials in response to sucrose.

Df(3L)ΔGr64 mutants expressing both Gr64fScer\UAS.cJa and Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 show a behavioural preference for sucrose over fructose that is very similar to that of wild-type flies. The wild-type frequency of action potentials in response to sucrose is also restored in these animals.

In contrast to wild-type flies, Df(3L)ΔGr64 mutant flies expressing Gr64fScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 display only a minimal increase in action potentials in response to maltose and they do not show a behavioural preference for maltose over fructose.

Df(3L)ΔGr64 mutants expressing both Gr64fScer\UAS.cJa and Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 show a behavioural preference for maltose over fructose that is very similar to that of wild-type flies. The wild-type frequency of action potentials in response to maltose is also restored in these animals.

Expression of Gr64fScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 partially restores the preference for glucose over fructose and action potentials in response to glucose in Df(3L)ΔGr64 mutants.

Co-expression of Gr64aScer\UAS.cJa and Gr64fScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 restores normal preference for glucose over fructose and wild-type frequencies of glucose dependent actin potentials.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Gr64fScer\UAS.cJa
Gr64fUAS.cJa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Jiao
Secondary FlyBase IDs
    References (2)