FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\dlg1WT.UAS.EGFP
Open Close
General Information
Symbol
Dmel\dlg1WT.UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0258363
Feature type
allele
Associated gene
Dmel\dlg1
Associated Insertion(s)
Carried in Construct
P{UAS-dlg1-EGFP}
Key Links
Transgenic product class
wild_type
(Lee and Wu, 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lee and Wu, 2010)
Mutagen
in vitro construct
(Lee and Wu, 2010)
Progenitor genotype
Carried in construct
P{UAS-dlg1-EGFP}
Cytology
Description

UAS regulatory sequences drive expression of wild-type dlg1 coding sequences tagged with EGFP.

(Lee and Wu, 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dlg1
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      dlg1WT.UAS.EGFP/Scer\GAL4Mef2.247 is a suppressor of abnormal neuroanatomy phenotype of slo1

      (Lee and Wu, 2010)
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Overexpression of dlg1WT.Scer\UAS.T:Avic\GFP-EGFP in the developing muscle under the control of Scer\GAL4Mef2.247 induces a more pronounced reduction in type B satellites (small boutons) in slo1 mutants. As a result, the numbers of remaining type B and type M satellites becomes similar, and there are fewer satellites in total. The number of mature boutons is significantly enhanced in slo1 larvae expressing post-synaptic dlg1WT.Scer\UAS.T:Avic\GFP-EGFP.

      (Lee and Wu, 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dlg1WT.Scer\UAS.T:Avic\GFP-EGFP
      dlg1WT.UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)