FB2026_02 , released June 18, 2026
Allele: Dmel\Irbp7B2
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General Information
Symbol
Dmel\Irbp7B2
Species
D. melanogaster
Name
FlyBase ID
FBal0258425
Feature type
allele
Associated gene
Dmel\Irbp
Associated Insertion(s)
Carried in Construct
Also Known As
ku707B2
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Johnson-Schlitz et al., 2007)
Progenitor genotype
P{SUPor-P}KG05068
(Johnson-Schlitz et al., 2007)
Cytology
Description

Deletion mutation.

(Johnson-Schlitz et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
complex_substitution
3R:11,411,082..11,412,513 [+]
Comment:

Deletion resulting from the imprecise excision of P{SUPor-P}KG05068. One deletion endpoint is from reported boundary sequences. The other boundary is in the P element and 12 bases of sequence of unknown origin (GTTAATCCCCTT) are present between them at the site of the insertion.

(Johnson-Schlitz et al., 2007, Johnson-Schlitz et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Flies expressing Hsap\HTT103Q.Ex1.Scer\UAS under the control of Scer\GAL4Rapgap1-OK6 in a Irbp7B2/IrbpEX8 background show an enhanced age-dependent decline in climbing ability compared to control flies.

      (Tamura et al., 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      7B2
      (Johnson-Schlitz et al., 2007)
      Irbp7B2
      (Beaucher et al., 2012, Johnson-Schlitz et al., 2007)
      Ku707B2
      (Tamura et al., 2011)
      ku707B2.2
      (Yu and McVey, 2010)
      ku707B2
      (White and Lambowitz, 2012)
      ku707b2
      (Beaucher et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)