FlyBase Allele Report: Dmel\Tsen54[MI03405]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Tsen54^MI03405

General Information

Symbol

Dmel\Tsen54^MI03405

Species

D. melanogaster

Name

FlyBase ID

FBal0260578

Feature type

allele

Associated gene

Associated Insertion(s)

Mi{MIC}Tsen54^MI03405

Carried in Construct

Key Links

Genomic Maps

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

Mi{MIC}Tsen54^MI03405

Cytology

Description

P-element insertion in exon 4 of Tsen54.

(Schmidt et al., 2022)

Allele components

Component

Use(s)

Inserted element

RMCE target element

Also carries

integrase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:12,205,089..12,205,089 [-]

(Bellen, 2011.5.31)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of pontocerebellar hypoplasia type 4

CEA

(Schmidt et al., 2022)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | third instar larval stage

(Schmidt et al., 2022)

abnormal neuroanatomy | third instar larval stage

(Schmidt et al., 2022)

decreased size | third instar larval stage

(Schmidt et al., 2022)

lethal - all die before end of P-stage

(Schmidt et al., 2022)

majority die during P-stage

(Schmidt et al., 2022)

Phenotype Manifest In

larval brain | third instar larval stage

(Schmidt et al., 2022)

Detailed Description

Statement

Reference

Tsen54^e02731 homozygous third instar larvae exhibit smaller brain lobes.

(Schmidt et al., 2022)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

36235

y¹ w^*; Mi{MIC}Tsen54^MI03405/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG5626^MI03405

(Bellen, 2011.5.31)

Tsen54²

(Schmidt et al., 2022)

Tsen54^MI03405

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections