FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\dila57
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General Information
Symbol
Dmel\dila57
Species
D. melanogaster
Name
FlyBase ID
FBal0262488
Feature type
allele
Associated gene
Dmel\dila
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Ma and Jarman, 2011)
Mutagen
Delta2-3 transposase
(Ma and Jarman, 2011)
Progenitor genotype
P{GT1}CG30001BG02674
(Ma and Jarman, 2011)
Caused by aberration
Df(2R)dila57
Cytology
Description

Imprecise excision of P{GT1}CG30001BG02674 resulting in a 0.9 kb deletion in which some of the CG30001 5'UTR and all/most of the DNA encoding the dila C-terminal coiled-coil domain is removed.

(Ma and Jarman, 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:9,823,017..9,823,917 [-]
Comment:

Approximate endpoints of a ~0.9 kb deletion resulting from the imprecise excision of P{GT1}CG30001BG02674.

(Ma and Jarman, 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes reach the adult stage and these mutant flies show uncoordinated behaviour. They have a dramatically reduced climbing ability in bang tests compared with wild type controls.

      (Ma and Jarman, 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      dila57
      (Ma and Jarman, 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)