FlyBase Allele Report: Dmel\EloC[HMS00128]

General Information

Symbol

Dmel\EloC^HMS00128

Species

D. melanogaster

Name

FlyBase ID

FBal0263130

Feature type

allele

Associated gene

Dmel\EloC

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00128}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.HMS00128}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00128

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

cell lethal | somatic clone, with Scer\GAL4^Act5C.PP

(Rougeot et al., 2013)

lethal, with Scer\GAL4^c684

(Rougeot et al., 2013)

lethal, with Scer\GAL4^nub.PU

(Rougeot et al., 2013)

lethal, with Scer\GAL4^OK10

(Rougeot et al., 2013)

lethal, with Scer\GAL4^rn.PU

(Rougeot et al., 2013)

lethal, with Scer\GAL4^salm.PU

(Rougeot et al., 2013)

lethal, with Scer\GAL4^sd.PU

(Rougeot et al., 2013)

lethal - all die during embryonic stage, with Scer\GAL4^da.PU

(Rougeot et al., 2013)

visible, with Scer\GAL4^nub.PU

(Rougeot et al., 2013)

visible, with Scer\GAL4^rn.PU

(Rougeot et al., 2013)

Phenotype Manifest In

wing, with Scer\GAL4^nub.PU

(Rougeot et al., 2013)

wing, with Scer\GAL4^rn.PU

(Rougeot et al., 2013)

wing disc | somatic clone | third instar larval stage, with Scer\GAL4^Act5C.PP

(Rougeot et al., 2013)

Detailed Description

Statement

Reference

Clones expressing EloC^HMS00128 under the control of Scer\GAL4^Act5C.PP are recovered less frequently than control clones in late third larval instar wing discs. The mutant clones are much smaller than the control clones are are always located at the disc periphery.

Escaper adults expressing EloC^HMS00128 under the control of either Scer\GAL4^rn.PU or Scer\GAL4^nub.PU at 20[o]C have tiny misshapen wings with severe growth and differentiation defects in the area of driver expression.

(Rougeot et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions