FlyBase Allele Report: Dmel\tkv[VDRC.cUa]

General Information

Symbol

Dmel\tkv^VDRC.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0263451

Feature type

allele

Associated gene

Dmel\tkv

Associated Insertion(s)

Carried in Construct

P{VDRC.tkv.U}

Key Links

Transgenic product class

RNAi_reagent

(Yuva-Aydemir et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Yuva-Aydemir et al., 2011)

Mutagen

in vitro construct

(Yuva-Aydemir et al., 2011)

Progenitor genotype

Carried in construct

P{VDRC.tkv.U}

Cytology

Description

UAS regulatory sequences drive expression of a tkv dsRNA.

(Yuva-Aydemir et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

tkv

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

tkv^VDRC.cUa, Scer\GAL80^Su(H).GBE, Scer\GAL4^NP7397 is a suppressor of abnormal cell number | adult stage phenotype of CG12744^VDRC.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

tkv^VDRC.cUa, Scer\GAL80^Su(H).GBE, Scer\GAL4^NP7397 is a suppressor of increased occurrence of cell division | adult stage phenotype of CG12744^VDRC.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

Scer\GAL4^repo.PU/tkv^VDRC.cUa is a suppressor of abnormal neuroanatomy phenotype of spin¹⁰⁴⁰³

(Yuva-Aydemir et al., 2011)

Phenotype Manifest In

Suppressor of

Statement

Reference

tkv^VDRC.cUa, Scer\GAL80^Su(H).GBE, Scer\GAL4^NP7397 is a suppressor of adult midgut epithelial cell phenotype of CG12744^VDRC.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

Scer\GAL4^repo.PU/tkv^VDRC.cUa is a suppressor of eye disc phenotype of spin¹⁰⁴⁰³

(Yuva-Aydemir et al., 2011)

Scer\GAL4^repo.PU/tkv^VDRC.cUa is a suppressor of glial cell phenotype of spin¹⁰⁴⁰³

(Yuva-Aydemir et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

The glial overmigration phenotype seen in spin¹⁰⁴⁰³ eye discs is significantly suppressed if the animals are also expressing tkv^VDRC.cUa under the control of Scer\GAL4^repo.PU.

(Yuva-Aydemir et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

tkv^VDRC.cUa

tkv^dsRNA

(Yuva-Aydemir et al., 2011)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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