FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Syn79
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General Information
Symbol
Dmel\Syn79
Species
D. melanogaster
Name
FlyBase ID
FBal0263513
Feature type
allele
Associated gene
Dmel\Syn
Associated Insertion(s)
?{}Syn79
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Godenschwege et al., 2004)
Mutagen
P-element activity
(Godenschwege et al., 2004)
Progenitor genotype
P{lacW}Syn-P2
(Godenschwege et al., 2004)
P{lacW}Syn-P1
(Godenschwege et al., 2004)
Associated Insertion(s)
?{}Syn79
Cytology
Description

P-element mutagenesis using the SynP1+P2 strain containing the P{lacW}SynP1 and P{lacW}SynP2 insertions has resulted in precise excision of the P{lacW}SynP2 insertion together with an imprecise excision of the P{lacW}SynP1 insertion. The imprecise excision results in the deletion of approximately 10000bp around the original insertion site (removing Syn exons 1-7) which is replaced by a 3kb fragment of unknown origin.

(Godenschwege et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants show no obvious anatomical defects in the synaptic neuropil of the adult brain.

      The number and ultrastructure of synaptic boutons at the neuroumuscular junction of muscles 12/13 and 6/7 is not significantly different in mutant larvae compared to wild type.

      The mean excitatory junction potential (EJP) amplitude at 0.5Hz stimulus frequency and the spontaneous miniature EJP amplitude and frequency at the mutant larval neuromuscular junction are normal.

      (Godenschwege et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The lesion in Syn79 may also affect the Timp gene.

      (Godenschwege et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Syn79
      (Blanco-Redondo et al., 2019, Godenschwege et al., 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)