FB2026_03 , released September 17, 2026
Allele: Dmel\Acbp-AnkGS1189
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General Information
Symbol
Dmel\Acbp-AnkGS1189
Species
D. melanogaster
Name
FlyBase ID
FBal0263553
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
GS1189
Key Links
Genomic Maps

Mutagen
    Nature of the Allele
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Cytology
    Description

    P{GSV1} insertion into protein-coding region of CG33714, which is also the 5' UTR of CG33713.

    Allele components
    Component
    Use(s)
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    anoxGS1189 larvae exhibit a significant reduction in weight gain, a delay in pupation, a significant decrease in feeding activities under both starvation (which increases the feeding rate of controls) and normal feeding conditions, and a significant decrease in mouth-hook contraction rates when larvae put into agar containing yeast or standard diet components while there is no change in mouth-hook contraction rates when larvae put into water compared to controls.

    anoxGS1189 adults exhibit a significant decrease in feeding activities, a decrease in sugar (sucrose and glucose) induced action potentials in taste sensilla and a significantly shorter life span with earlier mortality (more obvious in males than females) when compared to controls.

    While control larvae show a clear preference for soybean-containing food over corn-containing food and the amount of soybean food eaten increases linearly within a 60 minute period, larvae mutant for P{GSV1}CG33714GS1189 (which is associated with CG33713GS1189 and CG33714GS1189) do not show any such preference or any increased soybean food intake after 60 minutes.

    Unlike control larvae, which show a clear feeding preference for yeast extract food, larvae mutant for P{GSV1}CG33714GS1189 (which is associated with CG33713GS1189 and CG33714GS1189) do not show any significant feeding preference at all.

    When larvae are introduced to the centre of two wells, one filled with yeast-containing agar and the other filled with just agar, larvae mutant for P{GSV1}CG33714GS1189 (which is associated with CG33713GS1189 and CG33714GS1189) take much longer than controls to reach the yeast-containing agar.

    In contrast to controls, larvae mutant for P{GSV1}CG33714GS1189 (which is associated with CG33713GS1189 and CG33714GS1189) are not attracted to low concentrations of propionic acid or yeast.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Excision of P{GSV1} reverts of the feeding behaviour phenotype.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    Acbp-AnkGS1189
    CG33713GS1189
    anoxGS1189
    Name Synonyms
    Secondary FlyBase IDs
      References (2)