FB2026_03 , released September 17, 2026
Allele: Dmel\cpo462Lys
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General Information
Symbol
Dmel\cpo462Lys
Species
D. melanogaster
Name
FlyBase ID
FBal0263641
Feature type
allele
Associated gene
Dmel\cpo
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Schmidt et al., 2008)
Progenitor genotype
Cytology
Description

Ile/Lys polymorphism at amino acid 462 encoded in the 3' end of cpo exon 5.

(Schmidt et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      High-diapause lines, without exception, possess the cpo462Lys allele rather than the cpo462Ile allele.

      cpoBG02810/cpo462Lys is associated with higher diapause expression than cpoP3/cpo462Lys.

      cpo462Lys/cpoP3 is associated with higher diapause expression than cpo462Ile/cpoP3.

      cpo462Lys/cpoBG02810 is associated with higher diapause expression than cpo462Ile/cpoBG02810.

      Df(3R)cpo3.42/cpo462Lys is associated with higher diapause expression than Dp(3;3)cpo3.20/cpo462Lys.

      cpo462Lys/Df(3R)cpo3.42 is associated with higher diapause expression than cpo462Ile/Df(3R)cpo3.42.

      cpo462Lys/Dp(3;3)cpo3.20 is associated with higher diapause expression than cpo462Ile/Dp(3;3)cpo3.20.

      (Schmidt et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cpo462Lys
      (Schmidt et al., 2008)
      cpo462Lys
      (Schmidt et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)