FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dhc64CD12-5
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General Information
Symbol
Dmel\Dhc64CD12-5
Species
D. melanogaster
Name
FlyBase ID
FBal0263703
Feature type
allele
Associated gene
Dmel\Dhc64C
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Horne-Badovinac and Bilder, 2008)
Mutagen
ethyl methanesulfonate
(Horne-Badovinac et al., 2012, Horne-Badovinac and Bilder, 2008)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous Dhc64CD12-5 follicle cell clones, induced by driving Scer\FLP1Scer\UAS.cUa under the control of the Scer\GAL4e22c driver, show rounding and multilayering, predominantly at the posterior of the egg chamber. Gaps are seen in the epithelium.

      (Horne-Badovinac and Bilder, 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Dhc64CQ43-4

      (Horne-Badovinac and Bilder, 2008)

      Dhc64CN22-1

      (Horne-Badovinac and Bilder, 2008)
      Comments

      Introduction of a Dhc64C transgene is sufficient to rescue the lethality of Dhc64CD12-5 hemizygotes.

      (Horne-Badovinac and Bilder, 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Dhc64C[D12-5] complements GlK194.

      (Horne-Badovinac and Bilder, 2008)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      D12-5
      (Horne-Badovinac et al., 2012, Horne-Badovinac and Bilder, 2008)
      Dhc64CD12-5
      DhcD12-5
      (Horne-Badovinac and Bilder, 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)