Amino acid replacement: K38R.
UAS regulatory sequences drive expression of a mutated form of the coding sequence of Hsap\CSNK1E containing an amino acid substitution (K38R).
Expression of Hsap\CSNK1EK38R.Scer\UAS under the control of Scer\GAL4tim.Scer\UAS lengthens the period of circadian locomotor activity by two hours. Very few arrhythmic flies are seen.