FB2026_02 , released June 18, 2026
Allele: Ecol\lacZvvl.345
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General Information
Symbol
Ecol\lacZvvl.345
Species
E. coli
Name
FlyBase ID
FBal0265099
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{vvl-lacZ.345}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Sotillos et al., 2010)
Progenitor genotype
Carried in construct
P{vvl-lacZ.345}
Cytology
Description

Genomic sequence upstream of vvl that contains 4 putative Stat92E binding sites drives expression of lacZ under the control of a minimal Hsp70 promoter.

(Sotillos et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
vvl_vvl345
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Ecol\lacZvvl.345 is a non-suppressor of larval tracheal system phenotype of vvlunspecified

      (Sotillos et al., 2010)
      Other
      Statement
      Reference

      Ecol\lacZvvl.345, trh8 has epidermis phenotype

      (Sotillos et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The vvl expressing cells seen when Ecol\lacZvvl.345 is expressed in embryos in a trh8 mutant background fail to invaginate, remaining on the epidermal surface of the embryo.

      Expression of Ecol\lacZvvl.345 is unable to rescue the tracheal network defects seen in vvlunspecified mutant embryos.

      (Sotillos et al., 2010)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ecol\lacZvvl.345
      Name Synonyms
      Secondary FlyBase IDs
        References (3)