FB2026_03 , released September 17, 2026
Allele: Dmel\ManfΔ301
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General Information
Symbol
Dmel\ManfΔ301
Species
D. melanogaster
Name
FlyBase ID
FBal0265887
Feature type
allele
Associated gene
Dmel\Manf
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Magdalena et al., 2011)
Progenitor genotype
P{EP}EP3171
(Magdalena et al., 2011)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a 404bp deletion that removes the 5'UTR and first exon of Manf.

(Magdalena et al., 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:16,349,263..16,349,667 [+]
Comment:

404 bp deletion resulting from the imprecise excision of P{EP}EP3171 removes part of the Manf gene.

(Magdalena et al., 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes show polyphasic lethality, mainly in the embryonic and first larval instar stages (some second instar larval escapers are seen).

      (Magdalena et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      C18.2
      (Magdalena et al., 2011)
      ManfΔ301
      (Magdalena et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)