UAS regulatory sequences drive expression of a mutant form of abd-A in which the YPWM amino acid motif starting at position 109, the TDWM motif at position 115 and the ARRDR motif at position 208 have all been replaced with alanines. The construct is tagged with Tag:MYC.
Expressing abd-AW1+2A-RA.Scer\UAS.T:Hsap\MYC ubiquitously under the control of Scer\GAL4arm.PS causes homeotic transformations to A2 in segments anterior to the wild type A2 segment, as assessed by denticle pattern.