FlyBase Allele Report: Dmel\18w[g.UAS]

General Information

Symbol

Dmel\18w^g.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0267025

Feature type

allele

Associated gene

Dmel\18w

Associated Insertion(s)

Carried in Construct

P{UAS-18w.g}

Key Links

Transgenic product class

genomic_DNA

(Yagi et al., 2010)

wild_type

(Yagi et al., 2010)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Yagi et al., 2010)

wild_type

(Yagi et al., 2010)

Mutagen

in vitro construct

(Yagi et al., 2010)

Progenitor genotype

Carried in construct

P{UAS-18w.g}

Cytology

Description

UASt regulatory sequences drive expression of a genomic fragment containing the 18w coding sequence.

(Yagi et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

18w

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage, with Scer\GAL4^AM29

(Ward et al., 2015)

lethal, with Scer\GAL4^32B

(Yagi et al., 2010)

lethal, with Scer\GAL4^da.G32

(Yagi et al., 2010)

lethal, with Scer\GAL4^e22c

(Yagi et al., 2010)

lethal, with Scer\GAL4^ptc-559.1

(Yagi et al., 2010)

Phenotype Manifest In

adult abdomen, with Scer\GAL4^71B

(Yagi et al., 2010)

adult olfactory receptor neuron Or67a, with Scer\GAL4^AM29

(Ward et al., 2015)

eye, with Scer\GAL4^71B

(Yagi et al., 2010)

eye, with Scer\GAL4^GMR.PF

(Yagi et al., 2010)

eye, with Scer\GAL4^lz-gal4

(Yagi et al., 2010)

leg, with Scer\GAL4^dpp.PS

(Yagi et al., 2010)

leg disc, with Scer\GAL4^dpp.PS

(Yagi et al., 2010)

macrochaeta | ectopic, with Scer\GAL4^71B

(Yagi et al., 2010)

wing, with Scer\GAL4^dpp.PS

(Yagi et al., 2010)

wing disc, with Scer\GAL4^dpp.PS

(Yagi et al., 2010)

Detailed Description

Statement

Reference

Expression of 18w^g.Scer\UAS under the control of Scer\GAL4^AM29 results in lateral mistargeting of DM6 olfactory neuron axons.

(Ward et al., 2015)

Expression of 18w^g.Scer\UAS under the control of either Scer\GAL4^GMR.PF or Scer\GAL4^lz-gal4 generates a rough eye phenotype.

Expression of 18w^g.Scer\UAS under the control of Scer\GAL4^71B results in a closure defect in the adult abdomen, an extra bristle phenotype and a rough eye phenotype.

Expression of 18w^g.Scer\UAS under the control of Scer\GAL4^dpp.PS results in small wings that bifurcate along the anterior-posterior boundary

along with leg defects. This defect can be traced to the imaginal disc stage, where abnormal folding at the anterior-posterior boundary is found.

(Yagi et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

18w^g.Scer\UAS

18w^g.UAS

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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