FB2026_02 , released June 18, 2026
Allele: Dmel\dnt42.3
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General Information
Symbol
Dmel\dnt42.3
Species
D. melanogaster
Name
FlyBase ID
FBal0267697
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Nature of the Allele
Progenitor genotype
Cytology
Description

Imprecise excision of the P{EP} element in P{EP}dntEP2158 results in a 2322 bp deletion from positions 19360852 to 19363174. This deletions uncovers most of the first exon of dnt, including the transcription start site.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

A 2323bp deletion resulting from the imprecise excision of P{EP}dntEP2158 removes the first exon of dnt which included the translation start site.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In 8% of the hemisegments in dnt42.3 stage 16 embryos, lateral transverse muscles frequently bypass their normal attachment at the epidermis at muscle 12 and instead extend ventrally beyond muscle 13 and attach at a novel epidermal site located close to muscle fiber 7. The rest of the muscle pattern appears normal.

In 8% of the hemisegments in dnt42.3/Df(2L)Exel6043 stage 16 embryos, lateral transverse muscles frequently bypass their normal attachment at the epidermis at muscle 12 and instead extend ventrally beyond muscle 13 and attach at a novel epidermal site located close to muscle fiber 7.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
dnt42.3
Name Synonyms
Secondary FlyBase IDs
    References (1)