FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Act5CM44L.UAS.GFP
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General Information
Symbol
Dmel\Act5CM44L.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0267713
Feature type
allele
Associated gene
Dmel\Act5C
Associated Insertion(s)
Carried in Construct
P{UAS-Act5C.GFP.M44L}
Key Links
Transgenic product class
missense_variant
(Hung et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Hung et al., 2011)
Mutagen
in vitro construct
(Hung et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-Act5C.GFP.M44L}
Cytology
Description

UASt regulatory sequences drive expression of a Act5C mutant carrying an M44L amino acid substitution. The protein is tagged with GFP.

(Hung et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Act5C
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Act5CM44L.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4B11-98 in a Act5CG0420 mutant background leads to the suppression of the branching and shortening of bristles.

      (Hung et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of SelRC124S.Scer\UAS enhances the branched bristle phenotype seen upon Scer\GAL4B11-98-mediated expression of MicalScer\UAS.s, increasing both number and length of branches. Addition of Act5CM44L.Scer\UAS.T:Avic\GFP into this background abrogates the effect of SelRC124S.Scer\UAS.

      (Hung et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Act5CM44L.Scer\UAS.T:Avic\GFP
      Act5CM44L.UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (3)