FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AP-1σNIG.5864R
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General Information
Symbol
Dmel\AP-1σNIG.5864R
Species
D. melanogaster
Name
FlyBase ID
FBal0267843
Feature type
allele
Associated gene
Dmel\AP-1σ
Associated Insertion(s)
Carried in Construct
P{NIG.5864R}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Kametaka et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Kametaka et al., 2012)
Mutagen
in vitro construct
(Kametaka et al., 2012)
Progenitor genotype
Carried in construct
P{NIG.5864R}
Cytology
Description

UASt drives expression of a AP-1σ RNAi construct.

(Kametaka et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-5864R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4GMR.PU-mediated expression results in a normal eye.

      Scer\GAL4ey.PU-mediated expression results in a rough eye with irregular alignment of ommatidia and bristles. Ommatidia are of irregular sizes with excess/fewer rhabdomeres than normal; however, each ommatidium contains normally polarized photoreceptor cells, suggesting that the phenotypes are caused by defects in photoreceptor clustering during ommatidial formation.

      Most of the axons from the R7 and R8 photoreceptor cells in Scer\GAL4ey.PU, AP-1σNIG.5864R flies terminate in the medulla correctly, but some axons invade neighbouring columns or elongate beyond the M6 layer.

      Irregularly aligned and multiplied photoreceptor cells are observed in the eye discs of Scer\GAL4ey.PU, AP-1σNIG.5864R larvae.

      The specification of R8 neurons is disturbed in Scer\GAL4ey.PU, AP-1σNIG.5864R third instar larval discs.

      (Kametaka et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      AP-1σNIG.5864R
      Name Synonyms
      Secondary FlyBase IDs
        References (2)