FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Alas3b
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General Information
Symbol
Dmel\Alas3b
Species
D. melanogaster
Name
FlyBase ID
FBal0268435
Feature type
allele
Associated gene
Dmel\Alas
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Shaik et al., 2012)
Mutagen
P-element activity
(Shaik et al., 2012)
Progenitor genotype
P{SUPor-P}AlasKG10015
(Shaik et al., 2012)
Caused by aberration
Df(2R)Alas3b
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes the entire Alas coding region, all of CG34213 and part of or.

(Shaik et al., 2012)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous first instar larvae move actively in the egg case. The distribution of mitochondria appears normal in stage 17 mutant embryos and mitochondrial morphology is normal in mutant first instar larvae. Cuticle ultrastructure appears normal in mid-stage 17 mutant larvae. However, the cuticle of mutant first instar larvae is severely disorganised.

      (Shaik et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Alas3b
      CG30973b
      (Shaik et al., 2012)
      alas3b
      (Shaik et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)