FB2026_03 , released September 17, 2026
Allele: Dmel\lncRNA:let7C3.3ΔEcRE1-3
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General Information
Symbol
Dmel\lncRNA:let7C3.3ΔEcRE1-3
Species
D. melanogaster
Name
FlyBase ID
FBal0268488
Feature type
allele
Associated gene
Dmel\lncRNA:let7C
Associated Insertion(s)
Carried in Construct
P{let7C.3.3ΔEcRE1-3}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Chawla and Sokol, 2012)
Progenitor genotype
Carried in construct
P{let7C.3.3ΔEcRE1-3}
Cytology
Description

CR43344 cDNA expression is driven by a 3.3kb fragment containing a mutant form of the 20E responsive portion of the CR43344 first intron. The three 13bp Ecdysone response elements (EcRE) sequences have been deleted.

(Chawla and Sokol, 2012)
Allele components
Component
Use(s)
Encoded product / tool
lncRNA:let7C
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      lncRNA:let7C3.3ΔEcRE1-3 fails to rescue Df(2L)let-7-CGKI

      (Chawla and Sokol, 2012)
      Comments

      Expression of let-7-C3.3ΔEcRE1-3 fails to rescue the dorsal muscle phenotypes seen in Df(2L)let-7-CGKI mutant pupae and adults. These flies also continue to display defects in motility, flight and fertility.

      (Chawla and Sokol, 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CR433443.3ΔEcRE1-3
      let-7-C3.3ΔEcRE1-3
      lncRNA:let7C3.3ΔEcRE1-3
      Name Synonyms
      Secondary FlyBase IDs
        References (1)