FB2025_05 , released December 11, 2025
Allele: Dmel\putNIG.7904R
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General Information
Symbol
Dmel\putNIG.7904R
Species
D. melanogaster
Name
FlyBase ID
FBal0268551
Feature type
allele
Associated gene
Dmel\put
Associated Insertion(s)
Carried in Construct
P{NIG.7904R}
Also Known As
putRNAi, UAS-putRNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Le and Wharton, 2012)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Le and Wharton, 2012)
Mutagen
in vitro construct
(Le and Wharton, 2012)
Progenitor genotype
Carried in construct
P{NIG.7904R}
Cytology
Description

UASt regulatory sequences drive expression of a put RNAi construct.

(Le and Wharton, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-7904R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adulthood-only expression of putNIG.7904R under the combined control of Scer\GAL4esg.PU and Gal80[ts] (induced by temperature shift from 18[o]C to 29[o]C) leads to increased numbers of presumptive intestinal progenitors/enteroblasts and enteroblasts (i.e. esg- and GBE+Su(H)-positive cells, respectively), as well as increased mitotic index (pH3-positive cells), in the adult posterior midgut, as compared to controls; the size of the polyploid cells expressing putNIG.7904R is smaller than fully differentiated enterocytes, indicating a defect in maturation.

      (Ma et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      putNIG.7904R
      putRNAi
      (Ma et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (8)