FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\droshaQ884X
Open Close
General Information
Symbol
Dmel\droshaQ884X
Species
D. melanogaster
Name
FlyBase ID
FBal0269714
Feature type
allele
Associated gene
Dmel\drosha
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Pressman et al., 2012)
Progenitor genotype
Cytology
Description

Nucleotide substitution: C?T.

(Pressman et al., 2012)

Amino acid replacement: Q884term.

(Pressman et al., 2012)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:7,935,223..7,935,223 [+]
Nucleotide change:

C7935223T

Reported nucleotide change:

C?T

Amino acid change:

Q884term | drosha-PA

Reported amino acid change:

Q884term

(Pressman et al., 2012)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  brain disease
      CEA
      (Barish et al., 2022)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous clones of early larval born anterodorsal projection neurons (adPNs) in the adult brain appear grossly normal.

      (Luhur et al., 2014)

      Eyes entirely mutant for droshaQ884X (generated using the eyFLP method) are small and mispatterned.

      (Pressman et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Q884X
      (Pressman et al., 2012)
      droshaQ884X
      (Barish et al., 2022, Luhur et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)