FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Adarhyp
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General Information
Symbol
Dmel\Adarhyp
Species
D. melanogaster
Name
FlyBase ID
FBal0269849
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dAdarhyp
Key Links
Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description

A w+mW.hs marker flanked by loxP sites has been inserted into intron 7 of Adar.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

RNA editing is greatly reduced in Adarhyp mutants (assayed through RNA editing of para).

Adarhyp mutant males exhibit relatively robust locomotor activity, with no obvious uncoordination.

In Adarhyp males, peaks of morning and evening activity are present but reduced in amplitude compared to controls. Anticipation of morning, but not night, is completely abolished.

Adarhyp males exhibit a 4-fold increase in the time taken to initiate courtship relative to controls. Despite this, the overall length of time spent courting does not significantly differ.

Courtship pulse songs from Adarhyp males often exhibit abnormal waveforms characterized by polycyclic pulses and additional peaks. This change in waveform is accompanied by alterations in several other song parameters, including a reduced number of pulses per song train, an increase pulse frequency, and a small but highly significant increase in the inter-pulse interval. There is also a striking variability in the Adarhyp pulse waveforms, even between distinct song trains from the same male.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (3)