FlyBase Allele Report: Dmel\woc[D2rvX1]

General Information

Symbol

Dmel\woc^D2rvX1

Species

D. melanogaster

Name

FlyBase ID

FBal0270094

Feature type

allele

Associated gene

Dmel\woc

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Noyes et al., 2011)

Progenitor genotype

woc^D2

(Noyes et al., 2011)

Cytology

Description

Amino acid replacement: P971S.

(Noyes et al., 2011)

Contains the P917S amino acid replacement seen in the woc^D2 allele, as well as a 4 amino acid deletion in the sixth zinc finger.

(Noyes et al., 2011)

Amino acid replacement: N833I.

(Noyes et al., 2011)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die (with woc⁴⁶⁸)

(Noyes et al., 2011)

partially lethal - majority die (with woc^rgl)

(Noyes et al., 2011)

sterile (with woc⁴⁶⁸)

(Noyes et al., 2011)

sterile (with woc^rgl)

(Noyes et al., 2011)

visible (with woc⁴⁶⁸)

(Noyes et al., 2011)

visible (with woc^rgl)

(Noyes et al., 2011)

Phenotype Manifest In

eye (with woc⁴⁶⁸)

(Noyes et al., 2011)

eye (with woc^rgl)

(Noyes et al., 2011)

wing (with woc⁴⁶⁸)

(Noyes et al., 2011)

wing (with woc^rgl)

(Noyes et al., 2011)

wing vein (with woc⁴⁶⁸)

(Noyes et al., 2011)

wing vein (with woc^rgl)

(Noyes et al., 2011)

Detailed Description

Statement

Reference

woc^D2rvX1/woc^rgl mutants survive poorly and exhibit multiple phenotypic defects, including downturned wings, lack of wing veins, slightly rough eyes and sterility.

woc^D2rvX1/woc⁴⁶⁸ mutants survive poorly and exhibit multiple phenotypic defects, including downturned wings, lack of wing veins, slightly rough eyes and sterility.

(Noyes et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

woc^D2rvX1

(Noyes et al., 2011)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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