velo^LL05207 mutants exhibit projection neuron dendrite targeting defects.

velo^LL05207 mutant neuroblast clones exhibit several defects. First, the number of neurons is reduced from an average of 35 ad projection neurons in wild-type to 5 neurons in velo^LL05207 mutant clones. Second, the overall dendritic mass is reduced and disorganised. Third, dendrites aberrantly innervate the wrong glomeruli within the antennal lobe, or ectopically project outside the antennal lobe.

velo^LL05207 mutant DL1 projection neurons exhibit defects in axon morphology. Axons extend as wild-type and always reach the end of the lateral horn, but only form 0-2 collaterals in the mushroom body calyx, and often have a missing or shorter dorsal branch in the lateral horn. These axonal phenotypes are independent of the phenotypic class of dendrite mistargeting.