FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Zzzz\Poly-AlaA7.UAS.EGFP,Tag:NLS(SV40-largeT)
Open Close
General Information
Symbol
Zzzz\Poly-AlaA7.UAS.EGFP,Tag:NLS(SV40-largeT)
Species
a. artificial
Name
FlyBase ID
FBal0276826
Feature type
allele
Associated gene
Zzzz\Poly-Ala
Associated Insertion(s)
Carried in Construct
P{UAS-A7-EGFP.NLS}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Berger et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-A7-EGFP.NLS}
Cytology
Description

UASt drives expression of 7 polyalanine repeats that are tagged with EGFP and a nuclear localization signal (Tag:NLS(SV40-largeT)).

(Berger et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Zzzz\Poly-Ala
Tagged with
EGFP
Tag:NLS(SV40-largeT)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Zzzz\Poly-AlaA7.Scer\UAS.T:Avic\GFP-EGFP,T:SV40\nls2 under the control of Scer\GAL4ey.PB is non-toxic.

      (Berger et al., 2006)

      Expression of Zzzz\Poly-AlaA7.Scer\UAS.T:Avic\GFP-EGFP,T:SV40\nls2 under the control of either Scer\GAL4nrv2.PS, Scer\GAL4Mhc.PW or Scer\GAL4ey.PB does not lead to a reduction in lifespan compared to controls.

      Flies expressing Zzzz\Poly-AlaA7.Scer\UAS.T:Avic\GFP-EGFP,T:SV40\nls2 under the control of Scer\GAL4nrv2.PS do not exhibit an impaired climbing response compared to controls.

      Expression of Zzzz\Poly-AlaA7.Scer\UAS.T:Avic\GFP-EGFP,T:SV40\nls2 under the control of Scer\GAL4ey.PB does not produce any eye morphology defects, either at 25[o]C or 29[o]C.

      (Berger et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Zzzz\Poly-AlaA7.Scer\UAS.T:Avic\GFP-EGFP,T:SV40\nls2 under the control of Scer\GAL4elav-C155 is unable to suppress the rhabdomere loss seen in flies expressing Hsap\HTTGMR.Q120.

      (Berger et al., 2006)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Avic\GFPA7.EGFP.Scer\UAS.T:Zzzz\Poly-Ala.T:SV40\nls2
      Zzzz\Poly-AlaA7.Scer\UAS.T:Avic\GFP-EGFP,T:SV40\nls-largeT
      Zzzz\Poly-AlaA7.Scer\UAS.T:Avic\GFP-EGFP,T:SV40\nls2
      Zzzz\Poly-AlaA7.UAS.EGFP,Tag:NLS(SV40-largeT)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0276693
      • FBal0265631
      References (4)