FB2026_02 , released June 18, 2026
Allele: Dmel\Pgant35ARNAi.UAS.WIZ
Open Close
General Information
Symbol
Dmel\Pgant35ARNAi.UAS.WIZ
Species
D. melanogaster
Name
FlyBase ID
FBal0277673
Feature type
allele
Associated gene
Dmel\Pgant35A
Associated Insertion(s)
Carried in Construct
P{UAS-Pgant35A.RNAi.WIZ}
Key Links
Transgenic product class
RNAi_reagent
(Tran et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Tran et al., 2012)
Mutagen
in vitro construct
(Tran et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Pgant35A.RNAi.WIZ}
Cytology
Description

UAS regulatory sequences drive expression of double-stranded RNA (dsRNA) as a snapback hairpin corresponding to an approximately 500 bp fragment of Pgant35A using a pWIZ vector.

(Tran et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Pgant35A
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Pgant35AdsRNA.Scer\UAS.WIZ under the control of Scer\GAL4αTub84B.PL results in complete loss of viability.

      Expression of Pgant35AdsRNA.Scer\UAS.WIZ in the respiratory system under the control of Scer\GAL4btl.PS results in a dramatic reduction in viability.

      Expression of Pgant35AdsRNA.Scer\UAS.WIZ in the embryonic mesoderm under the control of Scer\GAL4c179 results in lethality.

      Expression of Pgant35AdsRNA.Scer\UAS.WIZ in the embryonic mesoderm under the control of Scer\GAL4how-24B results in complete lethality.

      Expression of Pgant35AdsRNA.Scer\UAS.WIZ under the control of Scer\GAL4Bx-MS1096 does not result in wing blistering.

      (Tran et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Pgant35ARNAi.UAS.WIZ
      Pgant35AdsRNA.Scer\UAS.WIZ
      Pgant35AdsRNA.UAS.WIZ
      Name Synonyms
      Secondary FlyBase IDs
        References (2)