l(2)35Aa, l(2)br12, br12, pgant35, BG:DS01068.8
Gene model reviewed during 5.40
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pgant35A using the Feature Mapper tool.
Pgant35A transcripts are detected in males and females on northern blots. High levels are expressed in the ovary. Lower levels are observed in the testis and in the carcasses. Analysis of unfertilized eggs and early embryos reveals a strong maternal contribution. In situ hybridization during oogenesis reveals expression in germ cells and in follicle epithelia throughout oogenesis.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pgant35A in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Pgant35A l(2)35Aa
Source for merge of: l(2)35Aa CG7480
FlyBase curator comment: "l(2)35Aa" (FBgn0001970, Pgant35A, CG7480) is also referred to in FBrf0151358 as "dGalNAc-T1", but "l(2)35Aa" is not the same gene as the gene with the valid symbol "GalNAc-T1" in FlyBase, which is FBgn0034025, CG8182 described in FBrf0130686 (accession number AF218236).