FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES
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General Information
Name
POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES
Species
D. melanogaster
Symbol
PGANT
FlyBase ID
FBgg0000787
Date last reviewed
2020-02-03
Number of members
12
Description
Description
Polypeptide N-acetylgalactosaminyltransferase catalyze the transfer of N-Acetylgalactosamine (GalNAc) from UDP-GalNAc to serine and threonine acceptor sites and initiate mucin-type O-glycosylation. (Adapted from FBrf0151358 and FBrf0190815).
Notes on Group

CG7304 and CG7579 are excluded from the PGANT gene group because they lack the invariant DXH motif (DAQ in CG7304 and NGH in CG7579) and have alterations in other critical residues within the catalytic domain known to be essential for enzymatic activity (FBrf0190815).

Source Material
The POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES Gene Group has been compiled using the following publication(s): Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, and Schwientek et al., 2002 .
Key Gene Ontology (GO) terms
Molecular Function
polypeptide N-acetylgalactosaminyltransferase activity
Biological Process
protein O-linked glycosylation
Cellular Component
Enzymatic activity
Enzyme name (EC)
polypeptide N-acetylgalactosaminyltransferase (2.4.1.41)
Related Gene Groups
Parent group(s)
N-ACETYLGALACTOSAMINYLTRANSFERASES
Members (12)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)

[ CAZY:GlycosylTransferase Family 27](http://www.cazy.org/GT27.html)

Synonyms and Secondary IDs
Synonym(s)
Glycosyltransferase Family 27
Polypeptide N-Acetylgalactosaminyltransferase
Carbohydrate-binding module family 13
GalNAc-transferase
PGANT
CBM13
POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES
GT27 FAMILY OF N-ACETYLGALACTOSAMINYLTRANSFERASES
GT27
Secondary FlyBase ID(s)
References (7)