Open Close
General Information
Symbol
Df(2L)fn2
Species
D. melanogaster
Name
Deficiency (2L) formaldehyde induced
FlyBase ID
FBab0001815
Feature type
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

pu << bk1 << l(2)35Ab << Adh << bk2 << mol

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from non-inclusion of elB (FBrf0091422) Right limit of break 1 from inclusion of elA (FBrf0030161) Left limit of break 2 from inclusion of Adh (FBrf0030161) Right limit of break 2 from polytene analysis (FBrf0051930)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    NOT in combination with other aberrations

    Chromosome acts as a strong trans-suppressor of a physical interaction between tandemly duplicated copies of w+, an interaction that is required for the suppression of genes by z1.

    Homozygous embryos gastrulate normally and usually appear morphologically normal at the end of embryogenesis (a few show weak pigmentation).

    Stocks (2)
    Notes on Origin
    Discoverer

    Sofer.

     

    Selected as ADH null on 1-penten-3-ol.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2L)fn2 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2L)fn2 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. In addition, any suppression is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    Reported to delete Adhr in error; see FBrf0141768 for correction.

    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Df(2L)fn2
    Name Synonyms
    Deficiency (2L) formaldehyde induced
    Secondary FlyBase IDs
      References (21)