l(2)br36, l(2)35Dc, br36, SPT, anon- EST:Posey289
encodes Serine Palmitoyl-transferase (SPT), the first enzymatic step for synthesis of sphingolipids - neuromuscular junction, enriched in lipid rafts - facilitates glial ensheathment of peripheral nerves - suppresses dystrophic muscle phenotypes in a model of Duchenne muscular dystrophy
Gene model reviewed during 5.52
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\lace using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\lace in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.