FlyBase Aberration Report: Dmel\Df(2L)fn30

General Information

Symbol

Df(2L)fn30

Species

D. melanogaster

Name

Deficiency (2L) formaldehyde induced

FlyBase ID

FBab0001819

Feature type

chromosomal_deletion

Computed Cytological Breakpoints (relative to progenitor)

34D3-34D4;35C1

Features within 34D3--35C1

Sequenced Breakpoints (relative to progenitor)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

formaldehyde

(O'Donnell et al., 1977)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Ashburner et al., 1990, Gubb et al., 1990)

Cytological Breakpoints (relative to progenitor)

34D3-34D6;35C1-35C3

(O'Donnell et al., 1977)

34C6-34C7;35B9-35C1

(Ashburner et al., 1990, Gubb et al., 1990)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

kuz << bk1 << l(2)34Db << vas << bk2 << stc

Genetic mapping information

Comments

Right breakpoint around 12.5 kb in 35C walk of Lasko and Ashburner (1988, Nature 335: 611-17)

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0030161) Right limit of break 1 from inclusion of Sos (FBrf0038050) Left limit of break 2 from polytene analysis (FBrf0030161) Right limit of break 2 from polytene analysis (FBrf0051930)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Adc

(Ashburner et al., 1982, O'Donnell et al., 1977)

Adh

(Ashburner et al., 1982, O'Donnell et al., 1977)

Ankrd49

(Ashburner et al., 1982, O'Donnell et al., 1977)

Arpc1

(Ashburner et al., 1982)

Ciapin1

(Ashburner et al., 1982, O'Donnell et al., 1977)

(O'Donnell et al., 1977)

DCTN5-p25

(Ashburner et al., 1982, O'Donnell et al., 1977)

elA

(Ashburner et al., 1982, O'Donnell et al., 1977)

l(2)34Db

(Ashburner et al., 1982)

l(2)34Fc

(Ashburner et al., 1982, O'Donnell et al., 1977)

l(2)34Fd

(Ashburner et al., 1982, O'Donnell et al., 1977)

mol

(Ashburner et al., 1982, O'Donnell et al., 1977)

NimA

(Ashburner et al., 1982, O'Donnell et al., 1977)

NimC3

(Ashburner et al., 1982)

noc

(Ashburner et al., 1982, O'Donnell et al., 1977)

osp

(Ashburner et al., 1982)

Pburs

(Ashburner et al., 1982, O'Donnell et al., 1977)

Pgant35A

(Ashburner et al., 1982, O'Donnell et al., 1977)

PolG1

(Ashburner et al., 1982)

PolG2

(Ashburner et al., 1982)

Polr2C

(Ashburner et al., 1982)

(Eriksen et al., 2000, Ashburner et al., 1982, O'Donnell et al., 1977)

Rnmt

(Ashburner et al., 1982, O'Donnell et al., 1977)

Smg5

(Ashburner et al., 1982)

Sos

(Ashburner et al., 1982)

Su(H)

(Ashburner et al., 1982, O'Donnell et al., 1977)

Thg

(Ashburner et al., 1982, O'Donnell et al., 1977)

Partially deleted / disrupted

Molecular Data

Completely deleted

mRpS23

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

(Ashburner et al., 1982)

Cul3

(Ashburner et al., 1982)

CycE

(Ashburner et al., 1982)

lace

(Ashburner et al., 1982)

PolD3

(Ashburner et al., 1982, O'Donnell et al., 1977)

sna

(Ashburner et al., 1982)

stc

(Ashburner et al., 1982)

wor

(Ashburner et al., 1982)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Weakly suppresses the zeste phenotype in a z¹ w^11E4; Tp(1;2)TE35B homologue.

(Gubb et al., 1990)

No effect on In(1)w^m4h position-effect variegation.

(Wustmann et al., 1989)

NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

Chromosome acts as a weak trans-suppressor of a physical interaction between tandemly duplicated copies of w⁺, an interaction that is required for the suppression of genes by z¹.

(Gubb et al., 1990)

Stocks (2)

Bloomington

6068

Df(2L)fn30, pr¹ cn¹/CyO, Adh^nB

Kyoto

108582

Df(2L)fn30, pr¹ cn¹/CyO, Adh^nB

Notes on Origin

Discoverer

Sofer.

elected as ADH null on 1-penten-3-ol.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

The Df(2L)fn30 chromosome acts as a dominant strong suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

(Mason et al., 2004)

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

41623

(Eriksen et al., 2000)

Df(2L)fn30

Name Synonyms

Deficiency (2L) formaldehyde induced

Secondary FlyBase IDs

References (12)

Report Sections

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