FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term serine C-palmitoyltransferase activity ID (Ontology) GO:0004758 (Gene Ontology)
Definition Catalysis of the reaction: L-serine + H+ + palmitoyl-CoA = 3-dehydrosphinganine + CO2 + CoA.[ EC:2 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 serine C-palmitoyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | serine C-palmitoyltransferase activity       --
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  palmitoyltransferase activity
   |__C-palmitoyltransferase activity
       |__serine C-palmitoyltransferase activity  3 rec.
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Is a C-palmitoyltransferase activity
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Synonyms
  • "3-oxosphinganine synthetase activity" RELATED[ EC:2 ]
    "serine palmitoyltransferase" BROAD
    "SPT" RELATED[ EC:2 ]
Secondary IDs
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EC:2.3.1.50
KEGG_REACTION:R01281
MetaCyc:SERINE-C-PALMITOYLTRANSFERASE-RXN
Reactome:R-HSA-428127 "SPTLC complexes transfer acyl-CoA onto serine"
RHEA:14761