pen-1, l(2)23Ag, l(2)23AB6
Gene model reviewed during 5.47
Component of the gamma-secretase complex, a complex composed of a presenilin (Psn) homodimer, nicastrin (Nct), Aph-1 and Pen-2.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\aph-1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\aph-1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA has been made from templates generated with primers directed against this gene.
dsRNA made from a cDNA library with primers directed against this gene (+71-412) is used in S2 cells to assess the effect on Psn maturation.
Identification: identified in a screen for enhancers of presenilin hypomorphic alleles.