FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term protein processing ID (Ontology) GO:0016485 (Gene Ontology)
Definition Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
Also Known As "protein maturation by peptide bond cleavage" ; "protein maturation by peptide bond hydrolysis"
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      46
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 protein processing (all annotations which use CV term, excluding "NOT" statements)       5     46
     involved_in | protein processing       --      46
Spanning Tree (Parents/Children)
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gene expression
 |__protein maturation_____
protein metabolic process  |
 |__proteolysis____________|
 |__protein maturation_____|
                           protein processing  93 rec.
                            |__activation of plasma proteins involved in acute inflammatory response
                            |__CAAX-box protein processing 7 rec.
                            |__dibasic protein processing
                            |   |__arg-arg specific dibasic protein processing
                            |   |__lys-arg specific dibasic protein processing
                            |   |__lys-lys specific dibasic protein processing
                            |__mitochondrial protein processing 5 rec.
                            |__Notch receptor processing, ligand-independent
                            |__protein autoprocessing 6 rec.
                            |__protein processing in phagocytic vesicle
                            |   |__regulation of protein processing in phagocytic vesicle(+)
                            |__protein splicing 1 rec.
                            |   |__intein-mediated protein splicing 1 rec.
                            |   |__non-intein-mediated protein splicing
                            |__regulation of protein processing 5 rec.
                            |   |__negative regulation of protein processing(+) 1 rec.
                            |   |__positive regulation of protein processing(+) 2 rec.
                            |   |__regulation of peptide hormone processing(+) 1 rec.
                            |   |__regulation of plasminogen activation(+) 1 rec.
                            |   |__regulation of protein processing in phagocytic vesicle(+)
                            |__signaling receptor ligand precursor processing 20 rec.
                            |   |__cytokine precursor processing
                            |   |__neuropeptide processing 1 rec.
                            |   |__peptide hormone processing(+) 19 rec.
                            |__vacuolar protein processing 1 rec.
                            |__zymogen activation 9 rec.
                                |__plasminogen activation(+) 1 rec.
                                |__trypsinogen activation
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Is a proteolysis
protein maturation
Part of
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Synonyms
  • "peptidolysis during protein maturation" RELATED
    "protein maturation by peptide bond cleavage" EXACT
    "protein maturation by peptide bond hydrolysis" EXACT
    "protein maturation by proteolysis" RELATED
Secondary IDs
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Reactome:R-HSA-9033500 "TYSND1 cleaves peroxisomal proteins"