Beach1, EP2299, DBEACH1, Beached
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bchs using the Feature Mapper tool.
bchs protein is expressed in the embryonic CNS from stage 12 on. It is observed in the longitudinal connectives and in a subset of neuronal cell bodies that lie between the commissures including the aCC and RP2 motor neurons. It is also observed at low levels throughout the CNS, in muscles, and in some other tissues.
GBrowse - Visual display of RNA-Seq signalsView Dmel\bchs in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Beach1 bchs
Source for merge of Beach1 BcDNA:SD12984 was a shared cDNA ( date:030728 ).
bchs may have some role in determining cellular volume and/or proliferation in the brain.
Mutants demonstrate a reduced adult life span associated with age-dependent formation of protein aggregates throughout the CNS. Protein inclusions contain insoluble ubiquinated proteins and aggregates of Appl. Brains from older bchs mutants also show extensive neuronal apoptosis.
Identification: in a screen for genes which when overexpressed cause motorneuron pathfinding and or synaptogenesis errors.
Involved in endocytosis/membrane trafficking.