FB2025_05 , released December 11, 2025
Gene: Dmel\Rab11
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General Information
Symbol
Dmel\Rab11
Species
D. melanogaster
Name
Rab11
Annotation Symbol
CG5771
Feature Type
protein_coding_gene
FlyBase ID
FBgn0015790
Gene Model Status
Current
Stock Availability
31 publicly available
Gene Summary
Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

l(3)j2D1, Drab11, l(3)93Bi, Rab-protein 11, DmRab11

Key Links
Genomic Location
Cytogenetic map
93B12-93B13
Sequence location
Recombination map
3-70
RefSeq locus
NT_033777 REGION:21111408..21116146
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (66 terms)
Molecular Function (5 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
enables GTPase activating protein binding
inferred from physical interaction with FLYBASE:Crag; FB:FBgn0025864
(Xiong et al., 2012)
inferred from physical interaction with FLYBASE:Evi5; FB:FBgn0262740
(Laflamme et al., 2012)
enables GTPase activity
inferred from mutant phenotype
(Laflamme et al., 2012)
enables protein binding
inferred from physical interaction with FLYBASE:Sec5; FB:FBgn0266670
(Beronja et al., 2005)
inferred from physical interaction with FLYBASE:Rip11; FB:FBgn0027335
(Laflamme et al., 2012)
inferred from physical interaction with FLYBASE:Sbf; FB:FBgn0025802
(Jean et al., 2012)
enables protein-containing complex binding
inferred from physical interaction with FLYBASE:Sec15; FB:FBgn0266674
(Langevin et al., 2005)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables GTP binding
inferred from biological aspect of ancestor with PANTHER:PTN004663565
(GO Reference Genome Project, 2011-)
inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR005225
(InterPro Project Members, 2004-)
enables GTPase activity
inferred from electronic annotation with InterPro:IPR001806
(InterPro Project Members, 2004-)
inferred from biological aspect of ancestor with PANTHER:PTN004663565
(GO Reference Genome Project, 2011-)
Biological Process (40 terms)
Terms Based on Experimental Evidence (39 terms)
CV Term
Evidence
References
involved_in actin cytoskeleton organization
inferred from mutant phenotype
(Riggs et al., 2003)
involved_in actomyosin contractile ring contraction
inferred from mutant phenotype
(Giansanti et al., 2007)
involved_in adherens junction maintenance
inferred from mutant phenotype
(Bogard et al., 2007)
involved_in antimicrobial peptide secretion
inferred from mutant phenotype
(Sorvina et al., 2016)
involved_in border follicle cell migration
inferred from mutant phenotype
(Chen et al., 2012, Assaker et al., 2010)
involved_in cellularization
inferred from mutant phenotype
(Pelissier et al., 2003)
involved_in centrosome localization
inferred from mutant phenotype
(Jauffred et al., 2013)
involved_in chaeta development
inferred from mutant phenotype
(Khodosh et al., 2006)
involved_in compound eye development
inferred from genetic interaction with FLYBASE:bchs; FB:FBgn0043362
(Khodosh et al., 2006)
involved_in compound eye morphogenesis
inferred from mutant phenotype
(Alone et al., 2005)
involved_in cortical actin cytoskeleton organization
inferred from mutant phenotype
(Jean et al., 2012)
involved_in dorsal closure, amnioserosa morphology change
inferred from mutant phenotype
(Mateus et al., 2011)
involved_in dorsal closure, elongation of leading edge cells
inferred from mutant phenotype
(Mateus et al., 2011)
involved_in dorsal closure
inferred from mutant phenotype
(Sasikumar and Roy, 2009)
involved_in endocytic recycling
inferred from genetic interaction with FLYBASE:Rho1; FB:FBgn0014020
(Yashiro et al., 2014)
inferred from mutant phenotype
(Hu et al., 2022)
involved_in endocytosis
inferred from direct assay
(Emery et al., 2005)
inferred from mutant phenotype
(Dollar et al., 2002)
involved_in exosomal secretion
inferred from mutant phenotype
(Tsarouhas et al., 2023, Corrigan et al., 2014)
involved_in follicle cell of egg chamber development
inferred from mutant phenotype
(Jia et al., 2015)
involved_in fusome organization
inferred from mutant phenotype
(Lighthouse et al., 2008)
involved_in germ-line stem cell division
inferred from mutant phenotype
(Lighthouse et al., 2008)
involved_in germ-line stem cell population maintenance
inferred from mutant phenotype
(Bogard et al., 2007)
involved_in Golgi vesicle fusion to target membrane
inferred from mutant phenotype
(Giansanti et al., 2007)
acts_upstream_of liquid clearance, open tracheal system
inferred from mutant phenotype
(Tsarouhas et al., 2023)
involved_in male meiosis cytokinesis
inferred from mutant phenotype
(Giansanti et al., 2007)
involved_in mitotic cytokinesis
inferred from mutant phenotype
(Kakade et al., 2025)
involved_in oocyte development
inferred from mutant phenotype
(Bogard et al., 2007)
involved_in oocyte microtubule cytoskeleton polarization
inferred from mutant phenotype
(Dollar et al., 2002)
involved_in ovarian fusome organization
inferred from mutant phenotype
(Bogard et al., 2007)
involved_in positive regulation of Golgi to plasma membrane protein transport
inferred from mutant phenotype
(Xiong et al., 2012)
involved_in protein localization to membrane
inferred from direct assay
(Mavor et al., 2016)
involved_in Rab protein signal transduction
inferred from direct assay
(Laflamme et al., 2012)
involved_in regulation of pole plasm oskar mRNA localization
inferred from mutant phenotype
(Dollar et al., 2002, Jankovics et al., 2001)
involved_in regulation of synapse organization
inferred from mutant phenotype
(Khodosh et al., 2006)
involved_in rhabdomere development
inferred from mutant phenotype
(Satoh et al., 2005)
involved_in sensory organ precursor cell fate determination
inferred from mutant phenotype
(Emery et al., 2005)
involved_in spermatocyte division
inferred from mutant phenotype
(Giansanti et al., 2007)
involved_in symbiont entry into host cell
inferred from high throughput mutant phenotype
(Hodgson et al., 2019)
involved_in synaptic vesicle endocytosis
inferred from genetic interaction with FLYBASE:Vps35; FB:FBgn0034708
(Inoshita et al., 2017)
involved_in vesicle-mediated transport
inferred from mutant phenotype
(Jones et al., 2014)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in exocytosis
inferred from biological aspect of ancestor with PANTHER:PTN000633981
(GO Reference Genome Project, 2011-)
Cellular Component (22 terms)
Terms Based on Experimental Evidence (21 terms)
CV Term
Evidence
References
located_in autophagosome
inferred from direct assay
(SzatmĂ¡ri et al., 2014)
located_in cell pole
inferred from direct assay
(Robinett et al., 2009, Giansanti et al., 2007)
colocalizes_with centrosome
inferred from direct assay
(Emery et al., 2005)
located_in cleavage furrow
inferred from direct assay
(Belloni et al., 2012, Robinett et al., 2009, Giansanti et al., 2007)
located_in cytoplasmic vesicle
inferred from direct assay
(Kakade et al., 2025, Xiong et al., 2012)
located_in cytoplasm
inferred from direct assay
(Robinett et al., 2009, Giansanti et al., 2007, Alone et al., 2005)
located_in dense core granule membrane
inferred from direct assay
(Redhai et al., 2016)
located_in endosome
inferred from direct assay
(Emery et al., 2005)
located_in fusome
inferred from direct assay
(Lighthouse et al., 2008, Bogard et al., 2007)
located_in Golgi apparatus
inferred from direct assay
(Robinett et al., 2009, Giansanti et al., 2007)
colocalizes_with microtubule organizing center
inferred from direct assay
(Riggs et al., 2007)
located_in neuronal cell body
inferred from high throughput direct assay
(Chan et al., 2011)
located_in nuclear envelope
inferred from direct assay
(Giansanti et al., 2007)
located_in perinuclear region of cytoplasm
inferred from direct assay
(Giansanti et al., 2007)
located_in plasma membrane
inferred from high throughput direct assay
(Tan et al., 2009)
colocalizes_with recycling endosome
inferred from direct assay
(Gault et al., 2012)
located_in recycling endosome
inferred from direct assay
(Dong et al., 2024, West et al., 2015, Yashiro et al., 2014, Jean et al., 2012)
located_in spindle envelope
inferred from direct assay
(Robinett et al., 2009, Giansanti et al., 2007)
located_in synapse
inferred from high throughput direct assay
(Chan et al., 2011)
inferred from direct assay
(West et al., 2015)
located_in terminal bouton
inferred from direct assay
(Khodosh et al., 2006)
located_in trans-Golgi network transport vesicle
inferred from direct assay
(Satoh et al., 2005)
located_in vesicle
inferred from direct assay
(Mavor et al., 2016, Laflamme et al., 2012, Jiang et al., 2007)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
is_active_in Golgi apparatus
inferred from biological aspect of ancestor with PANTHER:PTN000633981
(GO Reference Genome Project, 2011-)
is_active_in recycling endosome
inferred from biological aspect of ancestor with PANTHER:PTN000633981
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
GTPase activity
RHEA 19669:
Summaries
Gene Snapshot
Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions. [Date last reviewed: 2019-03-14]
Gene Group (FlyBase)
RAB GTPASES -
The Rab family are members of the Ras superfamily of small GTPases. Rabs regulate vesicle trafficking including cargo selection, vesicle budding, transport, docking and targeting. They localize to different intracellular compartments directed by specific isoprenylation of C-terminal motifs. (Adapted from PMID:15731001).
Summary (Interactive Fly)

Rab family GTPase - required in endocytic recycling and in the organization of posterior membrane compartments during oogenesis - functions in membrane trafficking during furrow formation during cellularization - functions in post-Golgi transport of rhodopsin to the rhabdomeric membranes of photoreceptors, and in analogous transport processes in other cells

Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Rab11 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry O18335)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.44

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Rab11-RA
FBtr0084010
NM_134310
1815
214
Rab11-RB
FBtr0084011
NM_057822
1627
214
Additional Transcript Data and Comments
Reported size (kB)

1.595 (longest cDNA)

(Satoh et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Rab11-PA
FBpp0083413
24.2
214
5.42
O18335
NP_599137
AAF55850
Rab11-PB
FBpp0083414
24.2
214
5.42
O18335
NP_477170
AAN13849
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

214 aa isoforms: Rab11-PA, Rab11-PB
Additional Polypeptide Data and Comments
Reported size (kDa)

214 (aa)

(Sasamura et al., 1997, Satoh et al., 1997)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rab11 using the Feature Mapper tool.

External Data
Crossreferences
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-1.22

Transcript Expression
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
organism | ubiquitous
(Sasamura et al., 1997)
embryonic stage -- adult stage
(Sasamura et al., 1997)
Additional Descriptive Data

Rab11 is expressed in all developmental stages. It is ubiquitously expressed throughout the embryo.

(Sasamura et al., 1997)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 4 -- 5
organism

Comment: robust

(Sasikumar and Roy, 2009)
embryonic stage 5
primordial germ cell

Comment: homogeneously distributed

(Sasikumar and Roy, 2009)
embryonic stage 6 -- 10
cephalic furrow

Comment: in invaginating cells

(Sasikumar and Roy, 2009)
ventral furrow
(Sasikumar and Roy, 2009)
germ band
(Sasikumar and Roy, 2009)
embryonic stage 6 -- 15
amnioserosa
(Sasikumar and Roy, 2009)
embryonic stage 11 -- 15
embryonic epidermis | lateral
(Sasikumar and Roy, 2009)
embryonic stage 13 -- 14
tracheal dorsal trunk primordium
(Sasikumar and Roy, 2009)
embryonic stage 14 -- 16
larval ventral nerve cord
(Bhuin and Roy, 2009)
embryonic/larval hindgut
(Bhuin and Roy, 2009)
embryonic stage 16
embryonic/larval tracheal section
(Dong et al., 2013)
third instar larval stage
embryonic/larval salivary gland | punctate

Comment: polytene cells

(Sasikumar and Roy, 2009)
embryonic/larval anterior midgut | punctate
(Sasikumar and Roy, 2009)
embryonic/larval hindgut | punctate
(Sasikumar and Roy, 2009)
gastric caecum | punctate
(Sasikumar and Roy, 2009)
ring gland | granular
(Sasikumar and Roy, 2009)
embryonic/larval Malpighian tubule | granular
(Sasikumar and Roy, 2009)
embryonic/larval garland cell
• cytoplasm
(Sasikumar and Roy, 2009)
embryonic/larval optic lobe
(Sasikumar and Roy, 2009)
wing disc
(Sasikumar and Roy, 2009)
leg disc
(Sasikumar and Roy, 2009)
eye disc
(Sasikumar and Roy, 2009)
eye disc morphogenetic furrow
(Sasikumar and Roy, 2009)
ommatidium
(Sasikumar and Roy, 2009)
larval inner optic anlage
(Sasikumar and Roy, 2009)
larval outer optic anlage
(Sasikumar and Roy, 2009)
wandering third instar larval stage
eye-antennal disc | ubiquitous
(Alone et al., 2005)
ommatidial precursor cluster
(Alone et al., 2005)
pharate adult stage P8
ommatidial precursor cluster
(Wu et al., 2005)
adult stage | male
primary spermatocyte
(Giansanti et al., 2007)
ejaculatory bulb | punctate

Comment: in basal region

(Sasikumar and Roy, 2009)
anterior ejaculatory duct
• cytoplasm

Comment: throughout

(Sasikumar and Roy, 2009)
male accessory gland main cell | punctate
(Sasikumar and Roy, 2009)
male accessory gland secondary cell

Comment: continuous around the big vacuoles

(Sasikumar and Roy, 2009)
testis | ubiquitous
(Tiwari and Roy, 2008)
primary gonial cell
(Tiwari and Roy, 2008)
spermatocyte
(Tiwari and Roy, 2008)
male accessory gland | restricted
(Tiwari and Roy, 2008)
ejaculatory bulb
(Tiwari and Roy, 2008)
adult stage
lamina
(Alone et al., 2005)
rhabdomere of eye photoreceptor cell
(Alone et al., 2005)
eye photoreceptor cell
(Alone et al., 2005)
adult stage | female
spermatheca
• cytoplasm

Comment: throughout

(Sasikumar and Roy, 2009)
female fusome
(Bogard et al., 2007)
oogenesis & adult stage | female
main body follicle cell | apical
(Khanal et al., 2016)
oogenesis
germarium
(Tiwari and Roy, 2008)
oocyte | restricted
(Tiwari and Roy, 2008)
follicle cell
(Tiwari and Roy, 2008)
oogenesis stage S7
oocyte

Comment: in perinuclear compartment and cortical regions

(Sasikumar and Roy, 2009)
oogenesis stage S8
oocyte

Comment: in cortical regions and antero-dorsal and antero-ventral corners

(Sasikumar and Roy, 2009)
oogenesis stage S10
follicle cell

Comment: basal region

(Sasikumar and Roy, 2009)
oocyte

Comment: localizes to posterior pole

(Sasikumar and Roy, 2009)
oocyte | posterior
(Tiwari and Roy, 2008)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
• membrane
(Aradska et al., 2015)
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
Additional Descriptive Data

Punctate, cytoplasmic Rab11 protein expression is detected throughout the length of the testis. In the apical region, expression is detected in the gonial cells and spermatocytes, in secretory vacuolated cells at the apical tip of the accessory gland, and in the ejaculatory bulb. In the ovary Rab11 is observed in the germarium and throughout oogenesis. At stage S9, is is expressed in the cortical region of the oocyte and at stage S10B it is prominent at the posterior pole of the embryo and in follicle cells.

(Tiwari and Roy, 2008)

The detailed subcellular expression pattern of Rab11 during male meiosis is reported.

(Giansanti et al., 2007)

Rab11 protein is widely distributed in all ommatidial and antennal cells in the eye-antennal disc. In adults, Rab11 is detected in photoreceptor cells, primarily in the rhabdomeres, and in the lamina neuropil.

(Alone et al., 2005)

Rab11 and Sec15 partially colocalize in the developing rhabdomeres.

(Wu et al., 2005)
Marker for
 
Golgi trans cisterna
(Kitazawa et al., 2012)
Subcellular Localization
CV Term
Evidence
References
located_in autophagosome
inferred from direct assay
(SzatmĂ¡ri et al., 2014)
located_in cell pole
inferred from direct assay
(Robinett et al., 2009, Giansanti et al., 2007)
colocalizes_with centrosome
inferred from direct assay
(Emery et al., 2005)
located_in cleavage furrow
inferred from direct assay
(Belloni et al., 2012, Robinett et al., 2009, Giansanti et al., 2007)
located_in cytoplasmic vesicle
inferred from direct assay
(Kakade et al., 2025, Xiong et al., 2012)
located_in cytoplasm
inferred from direct assay
(Robinett et al., 2009, Giansanti et al., 2007, Alone et al., 2005)
located_in dense core granule membrane
inferred from direct assay
(Redhai et al., 2016)
located_in endosome
inferred from direct assay
(Emery et al., 2005)
located_in fusome
inferred from direct assay
(Lighthouse et al., 2008, Bogard et al., 2007)
located_in Golgi apparatus
inferred from direct assay
(Robinett et al., 2009, Giansanti et al., 2007)
colocalizes_with microtubule organizing center
inferred from direct assay
(Riggs et al., 2007)
located_in neuronal cell body
inferred from high throughput direct assay
(Chan et al., 2011)
located_in nuclear envelope
inferred from direct assay
(Giansanti et al., 2007)
located_in perinuclear region of cytoplasm
inferred from direct assay
(Giansanti et al., 2007)
located_in plasma membrane
inferred from high throughput direct assay
(Tan et al., 2009)
colocalizes_with recycling endosome
inferred from direct assay
(Gault et al., 2012)
located_in recycling endosome
inferred from direct assay
(Dong et al., 2024, West et al., 2015, Yashiro et al., 2014, Jean et al., 2012)
located_in spindle envelope
inferred from direct assay
(Robinett et al., 2009, Giansanti et al., 2007)
located_in synapse
inferred from high throughput direct assay
(Chan et al., 2011)
inferred from direct assay
(West et al., 2015)
located_in terminal bouton
inferred from direct assay
(Khodosh et al., 2006)
located_in trans-Golgi network transport vesicle
inferred from direct assay
(Satoh et al., 2005)
located_in vesicle
inferred from direct assay
(Mavor et al., 2016, Laflamme et al., 2012, Jiang et al., 2007)
Expression Deduced from Reporters
Reporter: P{PTT-GA}Rab11CA07717
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | female
germarium
• fusome
(Lighthouse et al., 2008)
Reporter: P{Rab11.T:GFP.D}
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | male & spermatogenesis
primary spermatocyte in meiotic telophase I
(Belloni et al., 2012)
secondary spermatocyte in meiotic telophase II
(Belloni et al., 2012)
Reporter: PBac{544.SVS-1}Rab11CPTI100051
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult brain

Comment: low expression througout adult brain

(Knowles-Barley, 2011.8.24)
Reporter: PBac{I-SceI(FRT.Rab11-GAL4.ORF(loxP.3xP3-RFP))}
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage
neuron of larval brain
(Chan et al., 2011)
glial cell | subset of larval brain
(Chan et al., 2011)
embryonic/larval salivary gland | restricted
(Jin et al., 2012, Chan et al., 2011)
neuron | subset of larval ventral nerve cord
(Chan et al., 2011)
wing disc
(Chan et al., 2011)
eye disc
(Chan et al., 2011)
leg disc
(Chan et al., 2011)
neuropil glial sheath
(Jin et al., 2012)
Bolwig organ | restricted
(Jin et al., 2012)
embryonic/larval mushroom body | intense
(Jin et al., 2012)
eye disc | restricted
(Jin et al., 2012)
embryonic/larval optic stalk surface glial cell
(Jin et al., 2012)
leg disc | restricted
(Jin et al., 2012)
wing disc | restricted
(Jin et al., 2012)
pupal stage P6 -- P7
neuron of pupal brain

Comment: 30-40h APF

(Chan et al., 2011)
mushroom body

Comment: 30-40h APF

(Chan et al., 2011)
neuropil glial sheath

Comment: 30-40h APF

(Jin et al., 2012)
glial cell of second optic chiasma

Comment: 30-40h APF

(Jin et al., 2012)
neuron of adult optic lobe

Comment: 30-40h APF

(Jin et al., 2012)
mushroom body | intense

Comment: 30-40h APF

(Jin et al., 2012)
eye photoreceptor cell | intense

Comment: 30-40h APF

(Jin et al., 2012)
adult stage
neuron of adult brain
(Chan et al., 2011)
adult mushroom body | intense
(Jin et al., 2012, Chan et al., 2011)
adult ensheathing glial cell
(Jin et al., 2012)
adult inner optic chiasma giant glial cell | intense
(Jin et al., 2012)
neuron of adult optic lobe
(Jin et al., 2012)
adult antennal lobe
(Jin et al., 2012)
adult insulin secreting cell of pars intercerebralis | faint
(Jin et al., 2012)
neuron of lamina
(Jin et al., 2012)
ellipsoid body | intense
(Jin et al., 2012)
fan-shaped body
(Jin et al., 2012)
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Rab11 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 23 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 48 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Rab11
Transgenic constructs containing regulatory region of Rab11
Aberrations (Deficiencies and Duplications) ( 9 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
cell lethal | recessive | somatic clone
lethal
lethal, with Scer\GAL4grh.D4
lethal, with Scer\GAL4pnr-MD237
lethal, with Scer\GAL4Rab11.ORF
lethal, with Scer\GAL4repo.PU
lethal (with Df(3R)e-R1)
lethal (with Rab1193Bi)
lethal (with Rab11EP3017)
lethal (with Rab11ETo3)
lethal (with Rab11ETo11)
lethal (with Rab11ex1)
lethal | embryonic stage | germline clone | recessive
lethal | recessive
lethal - all die before end of first instar larval stage | recessive
lethal - all die before end of larval stage (with Rab11EP3017)
lethal - all die before end of larval stage (with Rab11mo)
lethal - all die before end of larval stage | recessive
lethal - all die during embryonic stage | germline clone
lethal - all die during embryonic stage | recessive
lethal - all die during P-stage, with Scer\GAL4Mef2.PR
partially lethal
partially lethal, with Scer\GAL4tin.CΔ4
partially lethal - majority die
partially lethal - majority die (with Rab1193Bi)
partially lethal - majority die (with Rab11EP3017)
partially lethal - majority die (with Rab11ETo3)
partially lethal - majority die (with Rab11ETo11)
partially lethal - majority die (with Rab11j2D1)
partially lethal - majority die | recessive
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4αTub84B.PL
Sterility
Allele
female semi-fertile
female semi-sterile (with Rab1193Bi)
female semi-sterile (with Rab11j2D1)
female sterile
female sterile (with Rab1193Bi)
female sterile (with Rab11EP3017)
female sterile (with Rab11ETo3)
female sterile (with Rab11ETo11)
female sterile | germline clone
fertile
fertile, with Scer\GAL4αTub84B.PL
sterile | recessive
Other Phenotypes
Allele
abnormal cell migration, with Scer\GAL4c306
abnormal cell migration, with Scer\GAL4slbo.2.6
abnormal cell migration | oogenesis, with Scer\GAL4c306
abnormal cell polarity | oogenesis, with Scer\GAL4c306
abnormal cell shape | adult stage | female
abnormal cytokinesis | male
abnormal cytokinesis | male (with Rab1193Bi)
abnormal cytokinesis | male (with Rab11EP3017)
abnormal cytokinesis | male (with Rab11ETo3)
abnormal cytokinesis | male (with Rab11ETo11)
abnormal locomotor behavior | adult stage | female, with Scer\GAL4futsch-C380
abnormal locomotor behavior | larval stage, with Scer\GAL4futsch-C380
abnormal locomotor behavior | third instar larval stage, with Scer\GAL4C164
abnormal locomotor behavior | third instar larval stage, with Scer\GAL4VGlut1.PD
abnormal meiotic cell cycle | male
abnormal meiotic cell cycle | male (with Rab1193Bi)
abnormal meiotic cell cycle | male (with Rab11EP3017)
abnormal meiotic cell cycle | male (with Rab11ETo3)
abnormal meiotic cell cycle | male (with Rab11ETo11)
abnormal neuroanatomy (with Rab1193Bi)
abnormal neuroanatomy (with Rab11ex1)
abnormal neuroanatomy | adult stage, with Scer\GAL4Alp4-c507
abnormal neuroanatomy | larval stage
abnormal neuroanatomy | larval stage, with Scer\GAL4elav.PU
abnormal neuroanatomy | third instar larval stage, with Hsim\VP16AD.nrv2, Scer\GAL4DBD.wrapper.932i
abnormal neuroanatomy | third instar larval stage, with Scer\GAL4elav-C155
abnormal neuroanatomy | third instar larval stage, with Scer\GAL4GMR.PF
abnormal neuroanatomy | third instar larval stage, with Scer\GAL4sca-537.4
abnormal neuroanatomy | third instar larval stage, with Scer\GAL4VGlut1.PD
abnormal neurophysiology | adult stage | conditional, with Scer\GAL4ninaE.PT
abnormal neurophysiology | larval stage, with Scer\GAL4C57
abnormal neurophysiology | larval stage, with Scer\GAL4elav.PU
abnormal neurophysiology | third instar larval stage, with Scer\GAL4elav-C155
abnormal size | adult stage, with Scer\GAL4GMR.PF
abnormal size | adult stage, with Scer\GAL4hs.PB
abnormal size | third instar larval stage, with Scer\GAL4da.G32
decreased body size | larval stage, with Scer\GAL4grh.D4
increased cell death
increased cell death, with Scer\GAL4GMR.PF
increased cell death, with Scer\GAL4unspecified
increased cell death | third instar larval stage
increased cell number | adult stage | cell non-autonomous, with Scer\GAL4NP0001
increased cell number | male | third instar larval stage, with Scer\GAL4C587
increased cell number | P-stage | somatic clone, with Scer\GAL4Act5C.PP
increased occurrence of cell division | adult stage, with Scer\GAL4Delta-05151-G
increased occurrence of cell division | adult stage, with Scer\GAL4NP0001
increased occurrence of cell division | adult stage, with Scer\GAL4NP5130
majority die during embryonic stage (with Rab1193Bi)
majority die during embryonic stage (with Rab11j2D1)
some die during embryonic stage
some die during embryonic stage | germline clone
some die during embryonic stage | recessive
some die during first instar larval stage | recessive
some die during larval stage (with Rab11EP3017)
some die during larval stage (with Rab11mo)
some die during larval stage | recessive
visible
visible, with Scer\GAL4Bx-MS1096
visible, with Scer\GAL4Eq
visible, with Scer\GAL4GMR.PF
visible, with Scer\GAL4sca-537.4
visible | adult stage, with Scer\GAL4GMR.PF
visible | larval stage, with Scer\GAL4grh.D4
visible | recessive
visible | somatic clone
wild-type
Phenotype manifest in
Allele
acroblast (with Rab1193Bi)
acroblast (with Rab11ETo11)
actin cytoskeleton | embryonic stage (with Rab1193Bi)
actin cytoskeleton | embryonic stage (with Rab11j2D1)
adherens junction | somatic clone
adult ellipsoid body R-neuron, with Scer\GAL4Alp4-c507
adult midgut | adult stage, with Scer\GAL4Delta-05151-G
adult midgut | adult stage, with Scer\GAL4NP0001
adult midgut | adult stage, with Scer\GAL4NP5130
adult midgut epithelium, with Scer\GAL4NP0001
amnioserosa
amnioserosa (with Df(3R)e-R1)
border follicle cell, with Scer\GAL4c306
border follicle cell, with Scer\GAL4slbo.2.6
bouton (with Rab1193Bi)
bouton (with Rab11ex1)
centrosome, with Scer\GAL4neur-P72
chaeta, with Scer\GAL4Eq
chaeta & antenna
cleavage furrow (with Rab1193Bi)
cleavage furrow (with Rab11ETo11)
cone cell
contractile ring (with Rab1193Bi)
contractile ring (with Rab11ETo11)
cyst cell of testis | third instar larval stage, with Scer\GAL4C587
dorsocentral bristle, with Scer\GAL4sca-537.4
egg
egg | germline clone
egg chamber, with Scer\GAL4NP1624
egg chamber, with Scer\GAL4VP16.mat.αTub67C
egg chamber, with Scer\GAL4VP16.nanos.UTR, Scer\GAL4VP16.otu, Scer\GAL4nanos.PG
egg chamber | germline clone
egg chamber | somatic clone
ellipsoid body, with Scer\GAL4Alp4-c507
embryonic/first instar larval cuticle, with Scer\GAL4da.G32
embryonic/first instar larval cuticle, with Scer\GAL4en-e16E
embryonic/larval cell body glial cell | third instar larval stage, with Hsim\VP16AD.nrv2, Scer\GAL4DBD.wrapper.932i
embryonic/larval fat body | third instar larval stage, with Scer\GAL4SPARC-MI00329-GAL4
embryonic/larval hemocyte | increased number | third instar larval stage
embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4C57
embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4elav.PU
embryonic/larval neuromuscular junction | third instar larval stage, with Scer\GAL4elav-C155
embryonic/larval plasmatocyte, with Scer\GAL4Cg.PA
embryonic/larval posterior spiracle | larval stage, with Scer\GAL4grh.D4
embryonic/larval tracheal dorsal trunk, with Scer\GAL469B
embryonic/larval tracheal dorsal trunk | first instar larval stage, with Scer\GAL4grh.D4
embryonic dorsal epidermis
embryonic dorsal epidermis (with Df(3R)e-R1)
embryonic leading edge cell
embryonic leading edge cell, with Scer\GAL4en-e16E
embryonic leading edge cell (with Df(3R)e-R1)
enteroblast | adult stage | cell non-autonomous, with Scer\GAL4NP0001
epithelium, with Scer\GAL4NP1624
external sensory organ precursor cell I, with Scer\GAL4neur-P72
extracellular exosome, with Scer\GAL4dsx.KI
extracellular vesicle | decreased number, with Scer\GAL4elav.PU
eye, with Scer\GAL4GMR.PF
eye | pupal stage
eye disc
eye disc | larval stage | somatic clone, with Scer\GAL4Act5C.PP
eye photoreceptor cell
eye photoreceptor cell, with Scer\GAL4GMR.PF
eye photoreceptor cell | somatic clone
female germline cyst, with Scer\GAL4NP1624
female germline cyst | somatic clone
female germline stem cell | somatic clone
filamentous actin, with Scer\GAL4VP16.nanos.UTR, Scer\GAL4VP16.otu, Scer\GAL4nanos.PG
filamentous actin | oogenesis, with Scer\GAL4VP16.mat.αTub67C
follicle cell, with Scer\GAL4NP1624
follicle cell | somatic clone
fusome | germline clone
garland cell, with Scer\GAL4hs.PB
germarium, with Scer\GAL4NP1624
germline cell (with Rab1193Bi)
germline cell (with Rab11j2D1)
germline stem cell | germline clone
Golgi-associated vesicle (with Rab1193Bi)
Golgi-associated vesicle (with Rab11ETo11)
gonad | male | third instar larval stage, with Scer\GAL4C587
hypodermal muscle cell of A1-7 | third instar larval stage, with Scer\GAL4elav-C155
interommatidial bristle
interommatidial bristle, with Scer\GAL4GMR.PF
interommatidial bristle (with Rab11EP3017)
interommatidial bristle (with Rab11mo)
interommatidial bristle | somatic clone
interommatidial cell | P-stage | increased number | somatic clone, with Scer\GAL4Act5C.PP
intestinal stem cell | adult stage | cell non-autonomous, with Scer\GAL4NP0001
larval tracheal system | embryonic stage, with Rab11N124I.UAS, Scer\GAL4btl.PS
larval tracheal system | embryonic stage, with Rab11S25N.UASp.YFP, Scer\GAL4btl.PS
larval tracheal system | embryonic stage, with Scer\GAL4btl.PS
macrochaeta
macrochaeta (with Rab1193Bi)
macrochaeta (with Rab11EP3017)
macrochaeta (with Rab11ETo3)
macrochaeta (with Rab11ETo11)
macrochaeta (with Rab11j2D1)
male accessory gland secondary cell, with Scer\GAL4dsx.KI
male germline stem cell | third instar larval stage, with Scer\GAL4C587
mesonotum, with Scer\GAL4Eq
microchaeta
microchaeta (with Rab1193Bi)
microchaeta (with Rab11ex1)
multivesicular body, with Scer\GAL4hs.PB
multivesicular body & eye photoreceptor cell | somatic clone
Nebenkern
Nebenkern (with Rab1193Bi)
Nebenkern (with Rab11EP3017)
Nebenkern (with Rab11ETo3)
Nebenkern (with Rab11ETo11)
nephrocyte, with Scer\GAL4Ugt36A1.PK, Scer\GAL80ts.αTub84B
neuromuscular junction
NMJ bouton | increased number
NMJ bouton | increased number | larval stage, with Scer\GAL4elav.PU
nucleus | embryonic stage (with Rab1193Bi)
nucleus | embryonic stage (with Rab11j2D1)
nurse cell ring canal | somatic clone
ommatidium
ommatidium, with Scer\GAL4GMR.PF
ommatidium (with Rab11EP3017)
ommatidium (with Rab11mo)
ommatidium | third instar larval stage, with Scer\GAL4sca-537.4
oocyte, with Scer\GAL4VP16.mat.αTub67C
oocyte | germline clone
optic cartridge | third instar larval stage, with Scer\GAL4GMR.PF
photoreceptor | third instar larval stage, with Scer\GAL4sca-537.4
photoreceptor neuron, with Scer\GAL4hs.PB
plasma membrane, with Scer\GAL4SPARC-MI00329-GAL4
posterior scutellar bristle (with Rab1193Bi)
posterior scutellar bristle (with Rab11ex1)
presynaptic active zone | larval stage, with Scer\GAL4elav.PU
primary pigment cell
rhabdomere
rhabdomere, with Scer\GAL4hs.PB
rhabdomere | conditional, with Scer\GAL4ninaE.PT
rhabdomere | somatic clone
scutellar bristle, with Scer\GAL4sca-537.4
slit diaphragm, with Scer\GAL4Ugt36A1.PK, Scer\GAL80ts.αTub84B
spermatid
spermatid (with Rab1193Bi)
spermatid (with Rab11EP3017)
spermatid (with Rab11ETo3)
spermatid (with Rab11ETo11)
spindle (with Rab1193Bi)
spindle (with Rab11ETo11)
stalk follicle cell, with Scer\GAL4NP1624
stem cell fusome | somatic clone
synaptic vesicle | third instar larval stage, with Scer\GAL4da.G32
tormogen cell, with Scer\GAL4sca-537.4
tormogen cell | increased number, with Scer\GAL4sca-109-68
tracheal lumen | embryonic stage, with Rab11N124I.UAS, Scer\GAL4btl.PS
tracheal lumen | embryonic stage, with Rab11S25N.UASp.YFP, Scer\GAL4btl.PS
tracheal lumen | embryonic stage, with Scer\GAL4btl.PS
trichogen cell, with Scer\GAL4sca-109-68
type I bouton | larval stage, with Scer\GAL4elav.PU
wing, with Scer\GAL4bs-1348
wing, with Scer\GAL4Bx-MS1096
wing hair | increased number, with Scer\GAL4en-e16E
wing hair | pupal stage, with Scer\GAL4Act5C.PI
wing vein, with Scer\GAL4bs-1348
wing vein, with Scer\GAL4Bx-MS1096
yolk granule | absent, with Scer\GAL4VP16.mat.αTub67C
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (56)
Hsap\RAB11A
13 of 14
Yes
Yes
Hsap\RAB11B
10 of 14
No
Yes
1  
Hsap\RAB25
4 of 14
No
Yes
Hsap\RABL2A
2 of 14
No
Yes
Hsap\RABL2B
2 of 14
No
Yes
Hsap\RAB1A
1 of 14
No
No
Hsap\RAB1B
1 of 14
No
No
Hsap\RAB1C
1 of 14
No
No
Hsap\RAB2A
1 of 14
No
No
1  
Hsap\RAB2B
1 of 14
No
No
Hsap\RAB3A
1 of 14
No
No
Hsap\RAB3B
1 of 14
No
No
Hsap\RAB3C
1 of 14
No
No
Hsap\RAB3D
1 of 14
No
No
Hsap\RAB4A
1 of 14
No
No
Hsap\RAB4B
1 of 14
No
No
Hsap\RAB5A
1 of 14
No
No
1  
Hsap\RAB5B
1 of 14
No
No
Hsap\RAB5C
1 of 14
No
No
1  
Hsap\RAB6A
1 of 14
No
No
Hsap\RAB6B
1 of 14
No
No
Hsap\RAB7A
1 of 14
No
No
5  
Hsap\RAB7B
1 of 14
No
No
Hsap\RAB8A
1 of 14
No
No
1  
Hsap\RAB8B
1 of 14
No
No
Hsap\RAB9A
1 of 14
No
No
1  
Hsap\RAB9B
1 of 14
No
No
1  
Hsap\RAB10
1 of 14
No
No
1  
Hsap\RAB12
1 of 14
No
No
Hsap\RAB13
1 of 14
No
No
Hsap\RAB14
1 of 14
No
No
1  
Hsap\RAB15
1 of 14
No
No
Hsap\RAB17
1 of 14
No
No
Hsap\RAB18
1 of 14
No
No
1  
Hsap\RAB19
1 of 14
No
No
Hsap\RAB21
1 of 14
No
No
Hsap\RAB22A
1 of 14
No
No
Hsap\RAB23
1 of 14
No
No
1  
Hsap\RAB26
1 of 14
No
No
Hsap\RAB28
1 of 14
No
No
Hsap\RAB29
1 of 14
No
No
Hsap\RAB30
1 of 14
No
No
1  
Hsap\RAB31
1 of 14
No
No
Hsap\RAB32
1 of 14
No
No
1  
Hsap\RAB35
1 of 14
No
No
Hsap\RAB37
1 of 14
No
No
Hsap\RAB38
1 of 14
No
No
Hsap\RAB39A
1 of 14
No
No
1  
Hsap\RAB39B
1 of 14
No
No
4  
Hsap\RAB40A
1 of 14
No
No
Hsap\RAB40AL
1 of 14
No
No
Hsap\RAB40B
1 of 14
No
No
2  
Hsap\RAB40C
1 of 14
No
No
1  
Hsap\RAB42
1 of 14
No
No
Hsap\RAB43
1 of 14
No
No
1  
Hsap\RAN
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (43)
Rnor\Rab11a
13 of 14
Yes
Yes
Rnor\Rab11b
10 of 14
No
Yes
Rnor\Rab25
4 of 14
No
Yes
Rnor\Rabl2
2 of 14
No
Yes
Rnor\Rab1a
1 of 14
No
No
Rnor\Rab1b
1 of 14
No
No
Rnor\Rab2a
1 of 14
No
No
Rnor\Rab2b
1 of 14
No
No
Rnor\Rab3b
1 of 14
No
No
Rnor\Rab3d
1 of 14
No
No
Rnor\Rab4a
1 of 14
No
No
Rnor\Rab4b
1 of 14
No
No
Rnor\Rab5al1
1 of 14
No
No
Rnor\Rab5a
1 of 14
No
No
Rnor\Rab5b
1 of 14
No
No
Rnor\Rab5c
1 of 14
No
No
Rnor\Rab6a
1 of 14
No
No
Rnor\Rab7a
1 of 14
No
No
Rnor\Rab7b
1 of 14
No
No
Rnor\Rab8a
1 of 14
No
No
Rnor\Rab8b
1 of 14
No
No
Rnor\Rab9a
1 of 14
No
No
Rnor\Rab9b
1 of 14
No
No
Rnor\Rab12
1 of 14
No
No
Rnor\Rab13
1 of 14
No
No
Rnor\Rab14
1 of 14
No
No
Rnor\Rab18
1 of 14
No
No
Rnor\Rab19
1 of 14
No
No
Rnor\Rab22a
1 of 14
No
No
Rnor\Rab23
1 of 14
No
No
Rnor\Rab28
1 of 14
No
No
Rnor\Rab29
1 of 14
No
No
Rnor\Rab30
1 of 14
No
No
Rnor\Rab31
1 of 14
No
No
Rnor\Rab32
1 of 14
No
No
Rnor\Rab35
1 of 14
No
No
Rnor\Rab38
1 of 14
No
No
Rnor\Rab39a
1 of 14
No
No
Rnor\Rab42
1 of 14
No
No
Rnor\Rab43
1 of 14
No
No
Rnor\Ran
1 of 14
No
No
Rnor\Rasl2-9
1 of 14
No
No
Rnor\RGD1306195
1 of 14
No
No
Mus musculus (laboratory mouse) (45)
Mmus\Rab11a
13 of 14
Yes
Yes
Mmus\Rab11b
10 of 14
No
Yes
Mmus\Rab25
3 of 14
No
Yes
Mmus\Rabl2
2 of 14
No
Yes
Mmus\1700009N14Rik
1 of 14
No
No
Mmus\Rab1a
1 of 14
No
No
1  
Mmus\Rab1b
1 of 14
No
No
Mmus\Rab2a
1 of 14
No
No
Mmus\Rab2b
1 of 14
No
No
Mmus\Rab3b
1 of 14
No
No
Mmus\Rab3d
1 of 14
No
No
Mmus\Rab4a
1 of 14
No
No
Mmus\Rab4b
1 of 14
No
No
Mmus\Rab5a
1 of 14
No
No
Mmus\Rab5b
1 of 14
No
No
Mmus\Rab5c
1 of 14
No
No
Mmus\Rab6a
1 of 14
No
No
Mmus\Rab7b
1 of 14
No
No
Mmus\Rab7
1 of 14
No
No
Mmus\Rab8a
1 of 14
No
No
Mmus\Rab8b
1 of 14
No
No
Mmus\Rab9b
1 of 14
No
No
Mmus\Rab9
1 of 14
No
No
Mmus\Rab10
1 of 14
No
No
Mmus\Rab12
1 of 14
No
No
Mmus\Rab13
1 of 14
No
No
Mmus\Rab14
1 of 14
No
No
Mmus\Rab18
1 of 14
No
No
Mmus\Rab19
1 of 14
No
No
Mmus\Rab21
1 of 14
No
No
Mmus\Rab22a
1 of 14
No
No
Mmus\Rab23
1 of 14
No
No
Mmus\Rab28
1 of 14
No
No
Mmus\Rab29
1 of 14
No
No
Mmus\Rab30
1 of 14
No
No
Mmus\Rab31
1 of 14
No
No
Mmus\Rab32
1 of 14
No
No
Mmus\Rab35
1 of 14
No
No
Mmus\Rab38
1 of 14
No
No
Mmus\Rab39b
1 of 14
No
No
Mmus\Rab39
1 of 14
No
No
Mmus\Rab42
1 of 14
No
No
Mmus\Rab43
1 of 14
No
No
Mmus\Ran
1 of 14
No
No
Mmus\Rasl2-9
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (36)
Xtro\rab11a
7 of 13
Yes
Yes
Xtro\rab11b.1
7 of 13
Yes
Yes
Xtro\rab11b.2
4 of 13
No
No
Xtro\uchl5
3 of 13
No
No
Xtro\rab25
2 of 13
No
Yes
Xtro\MGC69466
1 of 13
No
Yes
Xtro\rab1a
1 of 13
No
No
Xtro\rab2a
1 of 13
No
No
Xtro\rab2b
1 of 13
No
No
Xtro\rab3a
1 of 13
No
No
Xtro\rab3b
1 of 13
No
No
Xtro\rab3c
1 of 13
No
No
Xtro\rab3d
1 of 13
No
No
Xtro\rab4b
1 of 13
No
No
Xtro\rab5b
1 of 13
No
No
Xtro\rab5d
1 of 13
No
No
Xtro\rab6b
1 of 13
No
No
Xtro\rab8b
1 of 13
No
No
Xtro\rab12
1 of 13
No
No
Xtro\rab18
1 of 13
No
No
Xtro\rab19
1 of 13
No
No
Xtro\rab23
1 of 13
No
No
Xtro\rab26
1 of 13
No
No
Xtro\rab28
1 of 13
No
Yes
Xtro\rab29
1 of 13
No
No
Xtro\rab32
1 of 13
No
No
Xtro\rab35l
1 of 13
No
No
Xtro\rab35
1 of 13
No
No
Xtro\rab38
1 of 13
No
No
Xtro\rab39a
1 of 13
No
No
Xtro\rab39b
1 of 13
No
No
Xtro\rab40b
1 of 13
No
No
Xtro\rabl2b
1 of 13
No
Yes
Xtro\ran
1 of 13
No
No
Xtro\tmem255a
1 of 13
No
Yes
Xtro\XB5873314
1 of 13
No
No
Danio rerio (Zebrafish) (59)
Drer\rab11a
13 of 14
Yes
Yes
Drer\rab11ba
10 of 14
No
Yes
Drer\rab11bb
10 of 14
No
Yes
Drer\rab11al
8 of 14
No
Yes
Drer\rab25a
4 of 14
No
Yes
Drer\rab25b
3 of 14
No
Yes
Drer\rabl2
2 of 14
No
Yes
Drer\LOC555645
1 of 14
No
No
Drer\LOC100330257
1 of 14
No
No
Drer\LOC100536182
1 of 14
No
Yes
Drer\rab1aa
1 of 14
No
No
Drer\rab1ab
1 of 14
No
No
Drer\rab1ba
1 of 14
No
No
Drer\rab1bb
1 of 14
No
No
Drer\rab2a
1 of 14
No
No
Drer\rab3db
1 of 14
No
No
Drer\rab4a
1 of 14
No
No
Drer\rab4b
1 of 14
No
No
Drer\rab5aa
1 of 14
No
No
Drer\rab5ab
1 of 14
No
No
Drer\rab5b
1 of 14
No
No
Drer\rab5c
1 of 14
No
No
Drer\rab6a
1 of 14
No
No
Drer\rab6ba
1 of 14
No
No
Drer\rab6bb
1 of 14
No
No
Drer\rab7a
1 of 14
No
No
Drer\rab7b
1 of 14
No
No
Drer\rab8a
1 of 14
No
No
Drer\rab8b
1 of 14
No
No
Drer\rab9a
1 of 14
No
No
Drer\rab9b
1 of 14
No
No
Drer\rab10
1 of 14
No
No
Drer\rab12
1 of 14
No
No
Drer\rab13
1 of 14
No
No
Drer\rab14
1 of 14
No
No
Drer\rab14l
1 of 14
No
No
Drer\rab18a
1 of 14
No
No
Drer\rab18b
1 of 14
No
No
Drer\rab22a
1 of 14
No
No
Drer\rab23
1 of 14
No
No
Drer\rab30
1 of 14
No
No
Drer\rab31
1 of 14
No
No
Drer\rab32a
1 of 14
No
No
Drer\rab32b
1 of 14
No
No
Drer\rab35a
1 of 14
No
No
Drer\rab35b
1 of 14
No
No
Drer\rab38b
1 of 14
No
No
Drer\rab38c
1 of 14
No
No
Drer\rab39ba
1 of 14
No
No
Drer\rab39bb
1 of 14
No
No
Drer\rab41
1 of 14
No
No
Drer\rab42a
1 of 14
No
No
Drer\rab42b
1 of 14
No
No
Drer\rab43
1 of 14
No
No
Drer\ran
1 of 14
No
No
Drer\si:dkey-13a21.4
1 of 14
No
No
Drer\zgc:100918
1 of 14
No
No
Drer\zgc:162171
1 of 14
No
No
Drer\zgc:171927
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (24)
Cele\rab-11.1
12 of 14
Yes
Yes
Cele\rab-11.2
5 of 14
No
Yes
Cele\F11A5.3
1 of 14
No
No
Cele\F11A5.4
1 of 14
No
No
Cele\glo-1
1 of 14
No
No
Cele\K02E10.1
1 of 14
No
No
Cele\rab-1
1 of 14
No
No
Cele\rab-3
1 of 14
No
No
Cele\rab-5
1 of 14
No
No
Cele\rab-6.1
1 of 14
No
No
Cele\rab-6.2
1 of 14
No
No
Cele\rab-7
1 of 14
No
No
Cele\rab-8
1 of 14
No
No
Cele\rab-10
1 of 14
No
No
Cele\rab-14
1 of 14
No
No
Cele\rab-19
1 of 14
No
No
Cele\rab-21
1 of 14
No
No
Cele\rab-28
1 of 14
No
No
Cele\rab-30
1 of 14
No
No
Cele\rab-35
1 of 14
No
No
Cele\rab-37
1 of 14
No
No
Cele\rab-39
1 of 14
No
No
Cele\ran-1
1 of 14
No
No
Cele\unc-108
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (22)
Agam\AgaP_AGAP004559
10 of 12
Yes
Yes
Agam\AgaP_AGAP000433
1 of 12
No
No
Agam\AgaP_AGAP000671
1 of 12
No
No
Agam\AgaP_AGAP000841
1 of 12
No
No
Agam\AgaP_AGAP001211
1 of 12
No
No
Agam\AgaP_AGAP001617
1 of 12
No
No
Agam\AgaP_AGAP002092
1 of 12
No
No
Agam\AgaP_AGAP003028
1 of 12
No
No
Agam\AgaP_AGAP004146
1 of 12
No
No
Agam\AgaP_AGAP004204
1 of 12
No
No
Agam\AgaP_AGAP005255
1 of 12
No
No
Agam\AgaP_AGAP005393
1 of 12
No
No
Agam\AgaP_AGAP006159
1 of 12
No
No
Agam\AgaP_AGAP007096
1 of 12
No
No
Agam\AgaP_AGAP007654
1 of 12
No
No
Agam\AgaP_AGAP007699
1 of 12
No
No
Agam\AgaP_AGAP007901
1 of 12
No
No
Agam\AgaP_AGAP008419
1 of 12
No
No
Agam\AgaP_AGAP009846
1 of 12
No
No
Agam\AgaP_AGAP010875
1 of 12
No
No
Agam\AgaP_AGAP011363
1 of 12
No
No
Agam\AgaP_AGAP011565
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (65)
Atha\RABA1f
12 of 13
Yes
Yes
Atha\RABA1g
12 of 13
Yes
Yes
Atha\ArRABA1h
11 of 13
No
Yes
Atha\RABA1e
11 of 13
No
Yes
Atha\RABA1i
11 of 13
No
Yes
Atha\RABA1c
10 of 13
No
Yes
Atha\RABA1d
10 of 13
No
Yes
Atha\ARA-2
9 of 13
No
Yes
Atha\RABA1b
9 of 13
No
Yes
Atha\RABA2b
8 of 13
No
Yes
Atha\RAB11c
7 of 13
No
Yes
Atha\RABA2c
6 of 13
No
Yes
Atha\RABA2D
6 of 13
No
Yes
Atha\RABA4C
5 of 13
No
Yes
Atha\RABA4D
5 of 13
No
Yes
Atha\RABA4a
4 of 13
No
Yes
Atha\RABA4B
4 of 13
No
Yes
Atha\RABA5b
4 of 13
No
Yes
Atha\ARA4
3 of 13
No
Yes
Atha\RABA3
3 of 13
No
Yes
Atha\RABA5a
3 of 13
No
Yes
Atha\RABA5d
3 of 13
No
Yes
Atha\RABA5E
3 of 13
No
Yes
Atha\RABA6a
3 of 13
No
Yes
Atha\RABA6b
3 of 13
No
Yes
Atha\AT4G03156
2 of 13
No
Yes
Atha\AT4G08190
2 of 13
No
Yes
Atha\AT5G46025
2 of 13
No
Yes
Atha\RABA4E
2 of 13
No
Yes
Atha\ARA6
1 of 13
No
No
Atha\ARA7
1 of 13
No
No
Atha\AT3G57750
1 of 13
No
Yes
Atha\AT4G07524
1 of 13
No
Yes
Atha\AT5G59840
1 of 13
No
No
Atha\ATFP8
1 of 13
No
No
Atha\GB2
1 of 13
No
No
Atha\RA-5
1 of 13
No
No
Atha\RAB1A
1 of 13
No
No
Atha\RAB1C
1 of 13
No
No
Atha\RAB6A
1 of 13
No
No
Atha\RAB7A
1 of 13
No
No
Atha\RAB7B
1 of 13
No
No
Atha\RAB8
1 of 13
No
No
Atha\RAB8C
1 of 13
No
No
Atha\RAB18
1 of 13
No
No
Atha\RABB1a
1 of 13
No
No
Atha\RABB1C
1 of 13
No
No
Atha\RABE1c
1 of 13
No
No
Atha\RABE1e
1 of 13
No
No
Atha\RABG1
1 of 13
No
No
Atha\RABG3A
1 of 13
No
No
Atha\RABG3B
1 of 13
No
No
Atha\RABG3c
1 of 13
No
No
Atha\RABG3d
1 of 13
No
No
Atha\RABG3E
1 of 13
No
No
Atha\RABH1a
1 of 13
No
No
Atha\RABH1c
1 of 13
No
No
Atha\RABH1d
1 of 13
No
No
Atha\RABH1e
1 of 13
No
No
Atha\RAN2
1 of 13
No
No
Atha\RAN3
1 of 13
No
No
Atha\RAN4
1 of 13
No
No
Atha\RHA1
1 of 13
No
No
Atha\SGP1
1 of 13
No
Yes
Atha\SGP2
1 of 13
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (13)
Scer\YPT31
11 of 13
Yes
Yes
Scer\YPT32
10 of 13
No
Yes
Scer\GSP1
1 of 13
No
No
Scer\GSP2
1 of 13
No
No
Scer\SEC4
1 of 13
No
No
Scer\TEM1
1 of 13
No
Yes
Scer\VPS21
1 of 13
No
No
Scer\YPT1
1 of 13
No
No
Scer\YPT6
1 of 13
No
No
Scer\YPT7
1 of 13
No
No
Scer\YPT11
1 of 13
No
Yes
Scer\YPT52
1 of 13
No
No
Scer\YPT53
1 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (10)
Spom\ypt3
11 of 12
Yes
Yes
Spom\ryh1
1 of 12
No
No
Spom\spg1
1 of 12
No
Yes
Spom\spi1
1 of 12
No
No
Spom\ypt1
1 of 12
No
No
Spom\ypt2
1 of 12
No
No
Spom\ypt4
1 of 12
No
No
Spom\ypt5
1 of 12
No
No
Spom\ypt7
1 of 12
No
No
Spom\ypt71
1 of 12
No
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Rab11. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (33)
Rab2
3 of 13
Rab4
3 of 13
Rab39
3 of 13
Rab1
2 of 13
Rab3
2 of 13
Rab5
2 of 13
Rab6
2 of 13
Rab7
2 of 13
Rab8
2 of 13
Rab9Fb
2 of 13
Rab9
2 of 13
Rab10
2 of 13
Rab14
2 of 13
Rab19
2 of 13
Rab21
2 of 13
Rab23
2 of 13
Rab26
2 of 13
Rab30
2 of 13
Rab32
2 of 13
Rab35
2 of 13
RabX1
2 of 13
RabX2
2 of 13
CG4789
1 of 13
Rab9Db
1 of 13
Rab9D
1 of 13
Rab9E
1 of 13
Rab9Fa
1 of 13
Rab18
1 of 13
Rab27
1 of 13
Rab40
1 of 13
RabX5
1 of 13
Ran-like
1 of 13
Ran
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 4 )
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 9 )
    Allele
    Disease
    Interaction
    References
    Rab11N124I.UAS
    ameliorates  amyotrophic lateral sclerosis
    modeled by Hsap\TARDBPUAS.cHa
    (Deshpande et al., 2016)
    Rab11UAS.EGFP
    ameliorates  Huntington's disease
    modeled by Hsap\HTTQ93.ex1.UAS
    (Steinert et al., 2012)
    ameliorates  Parkinson's disease
    modeled by Hsap\SNCAUAS.cFa
    (Breda et al., 2015)
    modeled by Hsap\SNCAUAS.cKa
    (Breda et al., 2015)
    ameliorates  neurodegenerative disease
    modeled by Hsap\HTTQ93.ex1.UAS
    (Richards et al., 2011)
    ameliorates  cholera
    modeled by Vcho\ctxAUAS.cGa
    (Guichard et al., 2013)
    Rab11d01994
    ameliorates  Hermansky-Pudlak syndrome
    modeled by Blos1ex2
    (Cheli et al., 2010)
    Rab11RNAi.UAS.WIZ
    exacerbates  Parkinson's disease 2
    modeled by park13
    (Rai and Roy, 2022)
    Rab11UASp.YFP
    ameliorates  motor neuron disease
    modeled by scatHMS01910
    (Patel et al., 2020)
    Rab11S25N.UASp.YFP
    ameliorates  motor neuron disease
    modeled by scatHMS01910
    (Patel et al., 2020)
    exacerbates  motor neuron disease
    modeled by scatHMS01910
    (Wilkinson et al., 2021)
    DOES NOT ameliorate  Parkinson's disease
    modeled by Hsap\SNCAUAS.cKa
    (Breda et al., 2015)
    exacerbates  Charcot-Marie-Tooth disease type 4B1
    modeled by mtmG447D
    (Hu et al., 2022)
    Rab11Q70L.UASp.YFP
    ameliorates  Charcot-Marie-Tooth disease type 4B1
    modeled by mtmG447D
    (Hu et al., 2022)
    ameliorates  Parkinson's disease 2
    modeled by park13
    (Rai et al., 2023, Rai and Roy, 2022)
    ameliorates  Parkinson's disease 6
    modeled by Pink1HMS01707
    (Rai et al., 2023)
    Rab11KK108297
    model of  intestinal cancer
    is exacerbated by Ras85DV12.UAS
    (Nie et al., 2019)
    is exacerbated by wgUAS.cHa.Tag:HA
    (Nie et al., 2019)
    Rab11UAS.ORF.Tag:HA
    exacerbates  Alzheimer's disease 1
    modeled by Hsap\APP2xAPP.SP.UAS
    (Yu et al., 2020)
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    RAB11A; RAB11A, member RAS oncogene family
    13 of 14
    605570
        RAB11B; RAB11B, member RAS oncogene family
        10 of 14
        604198
           
          RAB25; RAB25, member RAS oncogene family
          4 of 14
          612942
              Functional Complementation Data
              Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
              Interactions
              Summary of Physical Interactions
              Interaction Browsers
              View in FlyBase Interactions Browser   View in MIST tool (external link)
              Please see the Physical Interaction reports below for full details
              protein-protein
              Physical Interaction
              Assay
              References
              Rab11 - Actin
              anti bait coimmunoprecipitation, western blot
              (Martin-Peña and Ferrus, 2020)
              Rab11 - Arf1
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - CG16826
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - CG31343
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - CG34133
              pull down, peptide massfingerprinting
              (Gillingham et al., 2014)
              Rab11 - CG5500
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - CG5521
              pull down, peptide massfingerprinting
              (Gillingham et al., 2014)
              Rab11 - CenB1A
              pull down, peptide massfingerprinting
              (Ramel et al., 2013)
              Rab11 - Cog7
              pull down, anti tag western blot, western blot
              (Frappaolo et al., 2017, Sechi et al., 2017)
              Rab11 - Crag
              enzymatic study, fluorescent dye label, anti tag coimmunoprecipitation, anti tag western blot
              (Xiong et al., 2012)
              Rab11 - Ehbp1
              anti tag coimmunoprecipitation, anti tag western blot
              (Giagtzoglou et al., 2012)
              Rab11 - Evi5
              pull down, anti tag western blot
              (Laflamme et al., 2012)
              Rab11 - Gdi
              pull down, peptide massfingerprinting, anti tag coimmunoprecipitation, experimental knowledge based
              (Rhee et al., 2014, Ramel et al., 2013)
              Rab11 - Hexo2
              pull down, peptide massfingerprinting
              (Gillingham et al., 2014)
              Rab11 - IKKε
              anti tag coimmunoprecipitation, anti tag western blot
              (Lin et al., 2020)
              Rab11 - Mdh2
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Moe
              pull down, anti tag western blot, peptide massfingerprinting, western blot
              (Ramel et al., 2013)
              Rab11 - Pgam1
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Phb2
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Pink1
              anti bait coimmunoprecipitation, western blot
              (Rai et al., 2023)
              Rab11 - Prx6c
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Rab2
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Rab4
              anti bait coimmunoprecipitation, western blot
              (Martin-Peña and Ferrus, 2020)
              Rab11 - RabGGTb
              enzymatic study, western blot
              (Charng et al., 2014)
              Rab11 - Rep
              pull down, peptide massfingerprinting
              (Ramel et al., 2013)
              Rab11 - Rip11
              pull down, peptide massfingerprinting, anti tag western blot, western blot, two hybrid
              (Laflamme et al., 2017, Laflamme and Emery, 2015, Gillingham et al., 2014, Ramel et al., 2013, Laflamme et al., 2012, Li et al., 2007)
              Rab11 - RpS15Ab
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Sbf
              anti tag coimmunoprecipitation, anti tag western blot
              (Jean et al., 2012)
              Rab11 - ScsβA
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Sec15
              pull down, western blot, autoradiography, anti tag western blot, anti bait coimmunoprecipitation
              (Chan et al., 2021, Langevin et al., 2005, Wu et al., 2005)
              Rab11 - Sec5
              anti bait coimmunoprecipitation, western blot, anti tag coimmunoprecipitation
              (Giansanti et al., 2015, Beronja et al., 2005, Langevin et al., 2005)
              Rab11 - TER94
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Tbc1d15-17
              pull down, peptide massfingerprinting
              (Ramel et al., 2013)
              Rab11 - Vha68-2
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - Vps35
              proximity ligation assay, fluorescence microscopy
              (Inoshita et al., 2017)
              Rab11 - Yp2
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - ccb
              anti bait coimmunoprecipitation, western blot
              (Martin-Peña and Ferrus, 2020)
              Rab11 - cher
              pull down, peptide massfingerprinting
              (Ramel et al., 2013)
              Rab11 - didum
              pull down, anti tag western blot, two hybrid, anti tag coimmunoprecipitation, autoradiography, peptide massfingerprinting
              (Ji et al., 2015, Ramel et al., 2013, Satoh et al., 2008, Li et al., 2007)
              Rab11 - dome
              anti tag coimmunoprecipitation, western blot
              (Chen et al., 2018)
              Rab11 - eIF3m
              pull down, peptide massfingerprinting
              (Ramel et al., 2013)
              Rab11 - fwd
              anti tag coimmunoprecipitation, anti tag western blot, two hybrid
              (Polevoy et al., 2009)
              Rab11 - hook
              anti tag coimmunoprecipitation, western blot, anti tag western blot
              (SzatmĂ¡ri et al., 2014)
              Rab11 - nuf
              pull down, peptide massfingerprinting, western blot, molecular weight estimation by staining, anti tag western blot, colocalization, fluorescence microscopy, inferred by author
              (Calero-Cuenca et al., 2016, Gillingham et al., 2014, Singari et al., 2014, Ramel et al., 2013, Otani et al., 2011, Riggs et al., 2003)
              Rab11 - park
              anti bait coimmunoprecipitation, western blot
              (Rai et al., 2023)
              Rab11 - pcs
              enzymatic study, fluorescence technology
              (Riedel et al., 2018)
              Rab11 - sau
              anti tag coimmunoprecipitation, western blot, pull down, anti tag western blot, surface plasmon resonance, predetermined participant
              (Sechi et al., 2017, Sechi et al., 2014)
              Rab11 - scu
              experimental knowledge based
              (Guruharsha et al., 2011)
              Rab11 - snz
              anti tag coimmunoprecipitation, anti tag western blot
              (Maruzs et al., 2023)
              Rab11 - spn-F
              anti tag coimmunoprecipitation, anti tag western blot, anti bait coimmunoprecipitation
              (Lin et al., 2020)
              Rab11 - sturkopf
              split luciferase complementation, luminiscence technology
              (Kolkhof et al., 2017)
              Rab11 - temp
              anti tag coimmunoprecipitation, anti tag western blot
              (Charng et al., 2014)
              Rab11 - vib
              anti tag coimmunoprecipitation, western blot, anti tag western blot, pull down
              (Frappaolo et al., 2017, Belloni et al., 2012)
              Rab11 - wun2
              anti tag coimmunoprecipitation, anti tag western blot, Identification by mass spectrometry
              (Gao et al., 2022)
              Rab11 - βTub85D
              experimental knowledge based
              (Guruharsha et al., 2011)
              Summary of Genetic Interactions
              Interaction Browsers
              View in FlyBase Interactions Browser   View in MIST tool (external link)
              Please look at the allele data for full details of the genetic interactions
              Starting gene(s)
              Interaction type
              Interacting gene(s)
              Reference
              Rab11
              suppressible
              bchs
              (Khodosh et al., 2006)
              Rab11
              enhanceable
              brun
              (Robinett et al., 2009)
              Rab11
              suppressible
              bsk
              (Tiwari and Roy, 2009)
              Rab11
              enhanceable
              ccb
              (Martin-Peña and Ferrus, 2020)
              Rab11
              enhanceable
              egr
              (Tiwari and Roy, 2009)
              Rab11
              enhanceable
              gish
              (Gault et al., 2012)
              Rab11
              suppressible
              msn
              (Tiwari and Roy, 2009)
              Rab11
              enhanceable
              Nin
              (Zheng et al., 2016)
              Rab11
              enhanceable
              nuf
              (Emery et al., 2005)
              Rab11
              suppressible
              puc
              (Tiwari and Roy, 2009)
              Rab11
              enhanceable
              puc
              (Tiwari and Roy, 2009)
              Rab11
              suppressible
              rho
              (Yogev et al., 2010)
              Rab11
              suppressible
              ru
              (Yogev et al., 2010)
              Rab11
              enhanceable
              scat
              (Wilkinson et al., 2021)
              Rab11
              enhanceable
              Tak1
              (Tiwari and Roy, 2009)
              Rab11
              enhanceable
              Traf4
              (Tiwari and Roy, 2009)
              Starting gene(s)
              Interaction type
              Interacting gene(s)
              Reference
              Acsl
              enhanceable
              Rab11
              (Liu et al., 2014)
              Atg1
              suppressible
              Rab11
              (Zhang et al., 2019)
              bchs
              enhanceable
              Rab11
              (Simonsen et al., 2007, Khodosh et al., 2006)
              Blos1
              suppressible
              Rab11
              (Cheli et al., 2010)
              brun
              enhanceable
              Rab11
              (Robinett et al., 2009)
              cactin
              suppressible
              Rab11
              (Miao et al., 2022)
              Crag
              suppressible
              Rab11
              (Xiong et al., 2012)
              ex|mtm
              suppressible
              Rab11
              (Hu et al., 2022)
              ft|mtm
              suppressible
              Rab11
              (Hu et al., 2022)
              fwd
              suppressible
              Rab11
              (Polevoy et al., 2009)
              grim
              enhanceable
              Rab11
              (Tiwari and Roy, 2009)
              hid
              enhanceable
              Rab11
              (Tiwari and Roy, 2009)
              IKKε
              enhanceable
              Rab11
              (Otani et al., 2011)
              mtm
              suppressible
              Rab11
              (Hu et al., 2022, Jean et al., 2012)
              mtm
              enhanceable
              Rab11
              (Hu et al., 2022)
              nuf
              enhanceable
              Rab11
              (Emery et al., 2005)
              Ocrl
              suppressible
              Rab11
              (Del Signore et al., 2017)
              Osbp
              suppressible
              Rab11
              (Ma et al., 2012)
              Rab5
              suppressible
              Rab11
              (Zhang et al., 2019)
              Rab7
              suppressible
              Rab11
              (Zhang et al., 2019)
              Rac1
              enhanceable
              Rab11
              (Assaker et al., 2010)
              Ras85D
              suppressible
              Rab11
              (Yogev et al., 2010)
              Rho1
              enhanceable
              Rab11
              (Warner and Longmore, 2009)
              rho
              suppressible
              Rab11
              (Zhang et al., 2019)
              RN-tre
              enhanceable
              Rab11
              (Houalla et al., 2010)
              scat
              suppressible
              Rab11
              (Patel et al., 2020)
              SH3PX1
              suppressible
              Rab11
              (Zhang et al., 2019)
              shot
              enhanceable
              Rab11
              (Sun et al., 2019)
              Syx17
              suppressible
              Rab11
              (Zhang et al., 2019)
              TBPH
              suppressible
              Rab11
              (Deshpande et al., 2016)
              Tm1
              enhanceable
              Rab11
              (Jankovics et al., 2001)
              Tm1|osk
              enhanceable
              Rab11
              (Jankovics et al., 2001)
              Vps35
              suppressible
              Rab11
              (Inoshita et al., 2017)
              External Data
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              DroID - A comprehensive database of gene and protein interactions.
              MIST (genetic) - An integrated Molecular Interaction Database
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Pathways
              Signaling Pathways (FlyBase)
              Metabolic Pathways
              FlyBase
              External Links
              External Data
              Linkouts
              KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              SignaLink - A signaling pathway resource with multi-layered regulatory networks.
              Class of Gene
              Genomic Location and Detailed Mapping Data
              Chromosome (arm)
              3R
              Recombination map
              3-70
              Cytogenetic map
              93B12-93B13
              Sequence location
              FlyBase Computed Cytological Location
              Cytogenetic map
              Evidence for location
              93B12-93B13
              Limits computationally determined from genome sequence between P{PZ}Atpα01164 and P{PZ}mod(mdg4)07038&P{lacW}mod(mdg4)L3101; (determined by in situ hybridisation)
              Experimentally Determined Cytological Location
              Cytogenetic map
              Notes
              References
              Location inferred from insertion in: Rab11[mo]
              (Alone et al., 2005)
              93B8-93B13
              (determined by in situ hybridisation)
              (Alone et al., 2005, Satoh et al., 1997)
              93C1-93C2
              (determined by in situ hybridisation)
              (Abdelilah-Seyfried et al., 2000, Spradling et al., 1999, Perrimon et al., 1996, BDGP Project Members, 1994-1999)
              93B8-93B13
              (Ozaki, 1996.4.3)
              93B-93B
              (determined by in situ hybridisation)
              (Sasamura, 1995)
              Experimentally Determined Recombination Data
              Location

              3-70

              (FlyBase, 2016)

              3-73.7

              (Comeron et al., 2012)
              Left of (cM)
              Right of (cM)
              Notes
              Stocks and Reagents
              Stocks (31)
              Genomic Clones (18)
               

              Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

              cDNA Clones (194)
               

              Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

              cDNA clones, fully sequenced
              BDGP DGC clones
              Other clones
              Drosophila Genomics Resource Center cDNA clones

              For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

              cDNA Clones, End Sequenced (ESTs)
              BDGP DGC clones
              Other clones
              RNAi and Array Information
              Linkouts
              DRSC - Results frm RNAi screens
              Antibody Information
              Laboratory Generated Antibodies
               

              polyclonal

              (Rai and Roy, 2022, Otsuka et al., 2019, Giansanti et al., 2015, Tanaka and Nakamura, 2008, Alone et al., 2005)
              Commercially Available Antibodies
               
              Cell Line Information
              Publicly Available Cell Lines
               
              Other Stable Cell Lines
               

              • New stable cell line derived from S2-unspecified : New stable cell line derived from S2-unspecified : CRISPR genome-edited cell lines were created carrying Sec71 mutations; the BFA-resistant M717L mutation or the BFA-hypersensitive F713Y mutation. These S2 cells were stably transfected with pMT-GalT-EGFP-T2A-tdTomato-Rab6 or pMT- GalT::EGFP-T2A-tdTomato::Rab11.

                (Fujii et al., 2020)
              Other Comments

              Loss of Rab11 leads to accumulation of autophagosomes and late endosomes. Rab11 protein translocates from recycling endosomes to autophagosomes in response to autophagy induction.

              (SzatmĂ¡ri et al., 2014)

              Rab11 is required for wls protein-containing exosome release at synaptic boutons.

              (Koles et al., 2012)

              An increase in the proportion of binucleated cells is seen following transfection of S2 cells with dsRNA made from templates generated with primers directed against this gene.

              (Kouranti et al., 2006)

              RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a greater than three-fold increase in AttA activity in response to heat-killed E.coli after ecdysone treatment in S2 cells.

              (Kleino et al., 2005)

              dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

              (Kiger et al., 2003)

              Rab11 has a role in endocytic recycling and in the organisation of posterior membrane compartments in the developing oocyte. Rab11 also has a role in the organisation of microtubule plus ends and osk mRNA localisation and translation.

              (Dollar et al., 2002)

              Identification: Enhancer trap screen designed to discover genes involved in the cellular aspects of defense mechanisms, as well as in melanotic tumor formation processes linked to blood cell disregulation.

              (Braun et al., 1997)

              Isolated from a Drosophila head cDNA library.

              (Satoh et al., 1997)

              The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation. Rab11 is required for germ cell viability or early oogenesis.

              (Perrimon et al., 1996)

              Identification: Sequence similarity to Rab3.

              (Sasamura et al., 1995)
              Relationship to Other Genes
              Source for database merge of

              Source for merge of: Rab11 l(3)j2D1

              (Dollar et al., 2000)

              Source for merge of: Rab11 l(3)93Bi

              (Jankovics et al., 2001)
              Additional comments
              Nomenclature History
              Source for database identify of

              Source for identity of: Rab11 CG5771

              (Gong, 1999.11)
              Nomenclature comments
              Etymology
              Synonyms and Secondary IDs (21)
              Reported As
              Symbol Synonym
              AAF55850
              (Armstrong, 2000)
              CG5771
              (Kolkhof et al., 2017, Dunst et al., 2015, Hosono et al., 2015, Schertel et al., 2013, Christis and Munro, 2012, Cammarato et al., 2011, Keleman et al., 2009.8.5, Perkins et al., 2009, Sinka et al., 2008, Derré et al., 2007, Zhang et al., 2007, Cermelli et al., 2006, Dorer et al., 2006, Colicelli, 2004, Verstreken and Bellen, 2000.9.4)
              DRAB11
              (Kohno et al., 1994)
              DRab11
              (Satoh et al., 1997)
              Dm Rab11
              (Jekely, 2003)
              DmRab11
              (Pereira-Leal and Seabra, 2001, Pereira-Leal and Seabra, 2001)
              Drab11
              (Sasamura, 1999.11.29, Sasamura et al., 1997, Sasamura et al., 1995)
              O18335
              (Rojas et al., 2012)
              RAB11
              (Buckley and St Johnston, 2022, Guan et al., 2020, Shaham, 2010, Dorer et al., 2006)
              Rab 11
              (Rice et al., 2021, Swetha et al., 2011)
              Rab-11
              (Kaczmarczyk and Kopp, 2011, Taniguchi et al., 2011)
              Rab-r11
              Rab11
              (Hatton et al., 2025, Kakade et al., 2025, Ku and Bilder, 2025, Luo et al., 2025, Richens et al., 2025, Sasaki et al., 2025, Collins et al., 2024, Davis et al., 2024, Dennis et al., 2024, Dong et al., 2024, Hendricks et al., 2024, Hodgson et al., 2024, Jiang, 2024, Kim et al., 2024, Meyer et al., 2024, Miao et al., 2024, Mira-Osuna and Borgne, 2024, Ochi et al., 2024, Pinot and Le Borgne, 2024, Rai et al., 2024, Rigato et al., 2024, Rui, 2024, Smith et al., 2024, Xu et al., 2024, Yu et al., 2024, Ascencio et al., 2023, Bertin et al., 2023, Bonello et al., 2023, Burghardt et al., 2023, Hossain et al., 2023, Khalili et al., 2023, Koehler and Huber, 2023, Li et al., 2023, Li et al., 2023, Madan et al., 2023, Maruzs et al., 2023, Mitchell et al., 2023, Nandy and Roy, 2023, Pradhan et al., 2023, Rai et al., 2023, Saha et al., 2023, Scholl et al., 2023, Titlow et al., 2023, Troost et al., 2023, Tsarouhas et al., 2023, Xu et al., 2023, Zhou et al., 2023, Zhou et al., 2023, Chaudhry et al., 2022, Chen and He, 2022, Ecovoiu et al., 2022, Gao et al., 2022, GonzĂ¡lez-RamĂ­rez et al., 2022, Hodgson et al., 2022, Jia et al., 2022, Kunduri et al., 2022, Lang et al., 2022, Linnemannstöns et al., 2022, Meyer et al., 2022, Miao et al., 2022, Milosavljevic et al., 2022, Ochi et al., 2022, Papagiannouli, 2022, Rai and Kumar Roy, 2022, Rai and Roy, 2022, Romanova-Michaelides et al., 2022, Sanchez-Lopez et al., 2022, Tanasic et al., 2022, van de Leemput et al., 2022, Wang et al., 2022, Alhadyian et al., 2021, Camelo and Luschnig, 2021, Chan et al., 2021, Furusawa and Emoto, 2021, Harnish et al., 2021, Lund et al., 2021, Ma and Brill, 2021, Martinez-Arroyo et al., 2021, Pizette et al., 2021, Ricolo et al., 2021, Tanaka et al., 2021, Wang et al., 2021, Witt et al., 2021, Yu et al., 2021, Aguilar-Aragon et al., 2020, Choubey et al., 2020, de Azevedo et al., 2020, Frank et al., 2020, Fujii et al., 2020, Gohel et al., 2020, Howe et al., 2020, Lin et al., 2020, Martin-Peña and Ferrus, 2020, Mathew et al., 2020, Nakamura et al., 2020, Nandy and Roy, 2020, Patel et al., 2020, Rui et al., 2020, Schwartz et al., 2020, Sorvina et al., 2020, Wen et al., 2020, White et al., 2020, Yu et al., 2020, Zhao et al., 2020, Bhuin and Roy, 2019, Blankenship, 2019.12.16, Hodgson et al., 2019, Jiang et al., 2019, Johnson and Andrew, 2019, Kampf et al., 2019, La Marca et al., 2019, Latcheva et al., 2019, Lattner et al., 2019, Lee and Chen, 2019, Mathiyalagan et al., 2019, Miao et al., 2019, Nie et al., 2019, Otsuka et al., 2019, Prince et al., 2019, Sim et al., 2019, Sinha et al., 2019, Tsai et al., 2019, Wang et al., 2019, Xu et al., 2019, Zhang et al., 2019, Artiushin et al., 2018, Ashley et al., 2018, Augustin et al., 2018, Chen et al., 2018, Gene Disruption Project members, 2018-, Hauswirth et al., 2018, Jin et al., 2018, Li et al., 2018, Pichaud, 2018, Salazar and Yamamoto, 2018, Thomas et al., 2018, Wang et al., 2018, Akbergenova and Littleton, 2017, Augustin et al., 2017, Beer and Wehman, 2017, BrĂ¼ser and Bogdan, 2017, Choubey and Roy, 2017, ColombiĂ© et al., 2017, Coutinho-Budd et al., 2017, Del Signore et al., 2017, Frappaolo et al., 2017, Galluzzi et al., 2017, Gao et al., 2017, Hsu and Drummond-Barbosa, 2017, Jewett et al., 2017, Kolkhof et al., 2017, Laflamme et al., 2017, Pinheiro et al., 2017, Schopf and Huber, 2017, Sechi et al., 2017, Tassetto et al., 2017, Zhang et al., 2017, Calero-Cuenca et al., 2016, Catrina et al., 2016, Caviglia et al., 2016, Deshpande et al., 2016, Iwanami et al., 2016, Johnson et al., 2016, Kato et al., 2016, Khanal et al., 2016, Luo et al., 2016, Mavor et al., 2016, Mukherjee et al., 2016, Neyen et al., 2016, Roman-Fernandez and Bryant, 2016, Sorvina et al., 2016, West and Harris, 2016, Woichansky et al., 2016, Zheng et al., 2016, Breda et al., 2015, Carvajal-Gonzalez et al., 2015, Chance and Bashaw, 2015, de Madrid et al., 2015, FarkaÅ¡ et al., 2015, Giansanti et al., 2015, Hosono et al., 2015, Jia et al., 2015, Laflamme and Emery, 2015, Le Droguen et al., 2015, Li et al., 2015, Miettinen and Björklund, 2015, Schweisguth, 2015, West et al., 2015, White et al., 2015, Zang et al., 2015, Zhang et al., 2015, Acharya et al., 2014, Chabu and Xu, 2014, Charng et al., 2014, Chung and Andrew, 2014, Corrigan et al., 2014, Couturier et al., 2014, de Vreede et al., 2014, Dodson et al., 2014, Garg and Wu, 2014, Gillingham et al., 2014, Gillingham et al., 2014, Gillingham et al., 2014, Gradilla et al., 2014, Hain et al., 2014, Issman-Zecharya and Schuldiner, 2014, Jones et al., 2014, Parsons et al., 2014, Politi et al., 2014, Sechi et al., 2014, Singari et al., 2014, SzatmĂ¡ri et al., 2014, Thomas and Strutt, 2014, Tsai et al., 2014, Valzania et al., 2014, Wang et al., 2014, Yashiro et al., 2014, Yu et al., 2014, Abdallah et al., 2013, Beckett et al., 2013, Chen et al., 2013, Dong et al., 2013, Fan et al., 2013, Guichard et al., 2013, Hermle et al., 2013, Ismat et al., 2013, Korkut et al., 2013, Kwon et al., 2013, Lerner et al., 2013, Pepperl et al., 2013, Sanchez-Garcia et al., 2013, Schertel et al., 2013, Solis et al., 2013, Song et al., 2013, Sotillos et al., 2013, Wan et al., 2013, Xiong and Bellen, 2013, Yamazaki et al., 2013, Yousefian et al., 2013, Zuo et al., 2013, Belloni et al., 2012, Bhuin and Kumar Roy, 2012, Bier and Guichard, 2012, Capilla et al., 2012, Chen et al., 2012, Dodson et al., 2012, Fabian and Brill, 2012, Fletcher et al., 2012, Gailite et al., 2012, Gault et al., 2012, Giagtzoglou et al., 2012, Giansanti et al., 2012, Gomez et al., 2012, Heider and Munson, 2012, Japanese National Institute of Genetics, 2012.5.21, Jean et al., 2012, Kitazawa et al., 2012, Koles et al., 2012, Laflamme et al., 2012, Ma et al., 2012, Nagaraj and Adler, 2012, Power et al., 2012, Sarpal et al., 2012, Singh and Mlodzik, 2012, Steinert et al., 2012, Wang et al., 2012, Xiong et al., 2012, Yamakawa et al., 2012, Zoller and Schulz, 2012, Banks et al., 2011, Ben El Kadhi et al., 2011, Benhra et al., 2011, Bhuin and Roy, 2011, Burgess et al., 2011, Cockcroft and Garner, 2011, Dalton et al., 2011, Daskalaki et al., 2011, Gould, 2011, Halbsgut et al., 2011, Leventis et al., 2011, Mateus et al., 2011, Michel et al., 2011, Otani et al., 2011, Richards et al., 2011, Rodal et al., 2011, Seong et al., 2011, Strutt et al., 2011, Sun et al., 2011, Tanaka et al., 2011, Yang et al., 2011, Yuva-Aydemir et al., 2011, Zhou et al., 2011, Becam et al., 2010, Benhra et al., 2010, Bhuin and Roy, 2010, Cheli et al., 2010, Cobreros-Reguera et al., 2010, Fernandez-Funez et al., 2010, Gervais and Casanova, 2010, Guichard et al., 2010, Haberman et al., 2010, Haglund et al., 2010, Houalla et al., 2010, Janssens et al., 2010, Karbowniczek et al., 2010, Li et al., 2010, Li et al., 2010, Mottola et al., 2010, Mukai et al., 2010, Muñoz-Descalzo et al., 2010, Murthy et al., 2010, Norum et al., 2010, Pirraglia et al., 2010, Stempfle et al., 2010, TiklovĂ¡ et al., 2010, Velichkova et al., 2010, Williamson et al., 2010, Windler and Bilder, 2010, Yogev et al., 2010, Akbar et al., 2009, Bhuin and Roy, 2009, Bhuin and Roy, 2009, Coumailleau et al., 2009, Fetting et al., 2009, Gupta et al., 2009, Kao and Megraw, 2009, Massarwa et al., 2009, Nagaraj and Banerjee, 2009, Polevoy et al., 2009, Robinett et al., 2009, Rodriguez-Fernandez and Dell'angelica, 2009, Roeth et al., 2009, Sasikumar and Roy, 2009, Tan et al., 2009, Thomas et al., 2009, Tiwari and Roy, 2009, Tuxworth et al., 2009, Venken et al., 2009, Warner and Longmore, 2009, Yan et al., 2009, Acharya et al., 2008, Cao et al., 2008, Denef et al., 2008, Harris and Tepass, 2008, Hossain et al., 2008, Kerman et al., 2008, Leibfried et al., 2008, Liebl and Featherstone, 2008, Miura et al., 2008, Morrison et al., 2008, Rodal et al., 2008, Satoh et al., 2008, Seppa et al., 2008, Shaye et al., 2008, Sinka et al., 2008, Strutt and Strutt, 2008, Tanaka and Nakamura, 2008, Tiwari and Roy, 2008, Blankenship et al., 2007, Buszczak et al., 2007, Chabu et al., 2007, Commisso and Boulianne, 2007, DerrĂ© et al., 2007, Dyer et al., 2007, Houalla and Rao, 2007, Jiang et al., 2007, Korolchuk et al., 2007, Li et al., 2007, Polevoy et al., 2007, Riggs et al., 2007, Roeth et al., 2007, Sasaki et al., 2007, Slack et al., 2007, Stuart et al., 2007, Tsarouhas et al., 2007, Tsruya et al., 2007, Wang et al., 2007, Zhang et al., 2007, Zhang et al., 2007, Bandyopadhyay et al., 2006, Bokel et al., 2006, Cermelli et al., 2006, Gallagher and Knoblich, 2006, Hagedorn et al., 2006, Khodosh et al., 2006, Kouranti et al., 2006, LaLonde et al., 2006, Maitra et al., 2006, Phillips and Thomas, 2006, Polo and Di, 2006, van IJzendoorn, 2006, Zhou et al., 2006, Alone et al., 2005, Beronja et al., 2005, Classen et al., 2005, Emery et al., 2005, Hutterer and Knoblich, 2005, Jafar-Nejad et al., 2005, Langevin et al., 2005, Lu and Bilder, 2005, Sevrioukov et al., 2005, Somers and Chia, 2005, Strigini, 2005, Wu et al., 2005, Lecuit, 2004)
              dRab11
              (Li et al., 2023, Ji et al., 2015)
              l(3)93Bi
              (Rawls, 1998.7.3)
              l(3)j2D1
              (Spradling et al., 1999, Braun et al., 1997, Perrimon et al., 1996, BDGP Project Members, 1994-1999)
              rab-11
              (Beckstead et al., 2007, Riechmann and Ephrussi, 2001)
              rab11
              (Smith et al., 2024, Hendricks et al., 2022, Hu et al., 2022, Thanh et al., 2020, Jouette et al., 2019, Krämer et al., 2019, Tsarouhas et al., 2019, Huang et al., 2018, Das and Cagan, 2017, Lammers et al., 2017, Huang et al., 2016, Liu et al., 2014, Jauffred et al., 2013, van den Brink et al., 2013, Giansanti and Fuller, 2012, Giansanti et al., 2012, Jin et al., 2012, Lesch and Page, 2012, Chan et al., 2011, Xu et al., 2011, Assaker et al., 2010, Hortsch et al., 2010, Silies and Klämbt, 2010, Lim and Kraut, 2009, Olswang-Kutz et al., 2009, Lighthouse et al., 2008, Xu et al., 2008, Akbar et al., 2007, Bogard et al., 2007, Devergne et al., 2007, Giansanti et al., 2007, Nurminsky, 2007, Simonsen et al., 2007, Xu and Cohen, 2007, Jaekel and Klein, 2006, Khodosh et al., 2006, LaLonde et al., 2006, Lecuit, 2004, Lecuit, 2003, Dollar et al., 2002, Abdelilah-Seyfried et al., 2000, Bellen, 2000.12.25, Dollar et al., 2000, Ozaki, 1996.4.3)
              rlr7
              (Eisenberg et al., 1990)
              Name Synonyms
              Rab-protein 11
              (Cammarato et al., 2011)
              Rab11
              lethal(3)93Bi
              Secondary FlyBase IDs
              • FBgn0004235
              • FBgn0011334
              Datasets (1)
              Study focus (1)
              Experimental Role
              Project
              Project Type
              Title
              • bait_protein
              Rab_Effectors_interaction_map
              Interaction map generated by purification of most Rab factors, with identification of copurifying effectors by mass spectrometry.
              Study result (0)
              Result
              Result Type
              Title
              External Crossreferences and Linkouts ( 64 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
              EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
              FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
              FlyMine - An integrated database for Drosophila genomics
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              MARRVEL_MODEL - MARRVEL (model organism gene)
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
              Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
              KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
              MIST (genetic) - An integrated Molecular Interaction Database
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              SignaLink - A signaling pathway resource with multi-layered regulatory networks.
              References (634)