FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term exosomal secretion ID (Ontology) GO:1990182 (Gene Ontology)
Definition The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.[ PubMed:10572093 PubMed:12154376 PubMed:16773132 PubMed:18617898 ]
Also Known As"exosomal secretory pathway" ; "extracellular vesicular exosome secretion" ; "multi-vesicular body fusion with plasma membrane" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 exosomal secretion (all annotations which use CV term, excluding "NOT" statements)
     involved_in | exosomal secretion
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vesicle-mediated transport
 |__exocytosis_____________________________
secretion by cell                          |
 |__exocytosis_____________________________|
vesicle localization                       |
 |__establishment of vesicle localization__|
establishment of localization in cell      |
 |__establishment of vesicle localization__|
establishment of organelle localization    |
 |__establishment of vesicle localization__|
extracellular vesicle biogenesis           |
 |__extracellular exosome biogenesis_______|
                                           exosomal secretion  10 rec.
                                            |__multivesicular body fusion to apical plasma membrane 2 rec.
                                            |__regulation of exosomal secretion
                                                |__negative regulation of exosomal secretion
                                                |__positive regulation of exosomal secretion
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Is a exocytosis
establishment of vesicle localization
Part of extracellular exosome biogenesis
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Synonyms
  • "exosomal protein secretion" NARROW[ PubMed:18617898 ]
    "exosomal secretory pathway" EXACT[ PubMed:18617898 ]
    "extracellular vesicular exosome secretion" EXACT
    "multi-vesicular body fusion with plasma membrane" EXACT
    "secretion of exosome" EXACT[ PubMed:18617898 ]
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