FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Rab11, Sec5
FlyBase ID
FBig0000099322
Interaction Network
Interactions Browser links
Rab11 network
Sec5 network
Reported Interactions
FBrf0187815-2.coIP.WB
Reference
Beronja et al., 2005
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rab11 

Rab11

bait

GFP tag

Sec5 

Sec5

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

sec5, but not sec6, could be detected in Rab11 immunoprecipitates.

(Beronja et al., 2005)

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Beronja et al., 2005)
FBrf0187815-3.coIP.WB
Reference
Beronja et al., 2005
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rab11 

Rab11

bait

GFP tag

Sec5 

Sec5

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

sec5, but not sec6, could be detected in Rab11 immunoprecipitates.

(Beronja et al., 2005)

Source was adult heads of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Beronja et al., 2005)
FBrf0190210-3.coIP.WB
Reference
Langevin et al., 2005
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rab11 

Rab11

bait
Sec5 

Sec5

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Langevin et al., 2005)
FBrf0230076-2.coIP.WB
Reference
Giansanti et al., 2015
Description
physical association
Assay
Collection
Source/Stage
testis / maleadult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rab11 

Rab11

bait

YFP

Rab11 
Rab11 
Sec5 

Sec5

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Rab11 
interaction domain Q70L
mutation decreasing interaction
aa 70

Q70L

Rab11 
interaction domain S25N
mutation decreasing interaction
aa 25

S25N

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was testes of wild-type fly line; bait produced from transgenic gene; prey produced from endodgenous gene.

(Giansanti et al., 2015)

Sec5 interacts with wildtype Rab11. This interaction can be reduced slightly by mutating Rab11 aa Q70L and strongly by mutating Rab11 aa S25N.

(Giansanti et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)